| Type | Description |
|---|---|
| Definition | ADAM metallopeptidase with thrombospondin type 1 motif 18 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:39:00 | Adamts18 links luminal hormone receptor signaling to basement membrane remodeling and stem cell activation. | 32218432 |
| 2020-04-04 11:55:00 | ADAMTS18 promoter methylation is a potential epigenetic biomarker. | 30417422 |
| 2019-09-21 12:08:00 | study suggests that ADAMTS18 is downregulated in cervical cancer and ADAMTS18 may serve as a potential prognostic biomarker for cervical cancer. | 28362704 |
| 2018-03-10 11:49:00 | In summary, we demonstrate that ADAMTS18 silencing in breast cancer is significantly correlated with promoter CpG methylation. ADAMTS18 acts as an antagonist of AKT and NF-kappaB signaling, further suppressing EMT and metastasis of breast cancer cells. | 28503860 |
| 2017-12-09 12:50:00 | This study showed that ADAMTS1, 8, and 18 are highly expressed in GC and its nodal metastases, suggesting important roles of these proteases in carcinogenesis and lymphatic metastasis. The findings from the present study indicate that these proteases may be promising candidates for novel and alternative treatments in GC (gastric cancer) | 28814085 |
| Type | IDs |
|---|---|
| Synonymous | ADAMTS21, KNO2, MMCAT |
| Gene |
UniProtKB-ID:
ATS18_HUMAN,
Q6ZN25_HUMAN,
Q2VYF7_HUMAN
UniprotKB:
Q8TE60,
Q6ZN25,
Q2VYF7
UniParc:
UPI0000EE66C7,
UPI000035E7B5,
UPI00006629D1,
UPI0000233610
EMBL:
AC009139,
BC063283,
AK131403,
AC010548,
AJ311903,
AY172951,
AC025284,
AK122677
Ensembl:
ENSG00000140873
KO:
hsa:170692
|
| Nucleutide sequences |
EMBL-CDS:
CAC83612.1,
BAC85503.1,
AAH63283.1,
BAD18550.1,
AAO45695.1
Ensembl_TRS:
ENST00000282849
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000282849
RefSeq:
XP_011521225.1,
NP_955387.1,
XP_016878477.1,
XP_011521226.1,
NP_001313287.1,
XP_016878478.1
|
| Others |
UniRef100:
UniRef100_Q2VYF7,
UniRef100_Q6ZN25,
UniRef100_Q8TE60
UniRef90:
UniRef90_Q6ZN25,
UniRef90_Q8TE60,
UniRef90_Q2VYF7
UniRef50:
UniRef50_A0A060VM48,
UniRef50_Q6ZN25,
UniRef50_Q8TE60
UniGene:
Hs.188746
CCDS:
CCDS10926.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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