Type | Description |
---|---|
Definition | nephrosis 2, podocin |
Date | Results | Publications |
---|---|---|
2021-03-13 13:18:00 | Proteolytic cleavage of Podocin by Matriptase exacerbates podocyte injury. | 32907879 |
2017-11-11 13:45:00 | While R140Q podocin mRNA expression was elevated, protein abundance was reduced by more than 50% within one week following induction | 29049388 |
2017-01-28 11:20:00 | Ubiquitin ligase Ubr4 is a key component of the podocin interactome purified from cultured podocytes and native glomeruli. Ubiquitylomic analysis of mouse glomeruli revealed that podocin is ubiquitylated at two lysine residues. Ubiquitylation of one podocin site, K301, do not only target podocin for proteasomal degradation, but may also affect stability and disassembly of the multimeric complex. | 26792178 |
2014-06-21 12:36:00 | ATP evokes activation of TRPC6 channels in podocytes through P2Y receptors, podocin, and generation of reactive oxygen species. | 24553432 |
2014-06-07 10:05:00 | the carboxyl terminus of podocin/MEC-2 has to be placed at the inner leaflet of the plasma membrane to mediate cholesterol binding and contribute to ion channel activity. | 24596097 |
Type | IDs |
---|---|
Synonymous | PDCN, SRN1 |
Gene |
UniProtKB-ID:
PODO_MOUSE,
C0LL94_MOUSE
UniprotKB:
Q91X05,
C0LL94
UniParc:
UPI0000022956
EMBL:
FJ715770,
AJ302048,
AK052746,
BC067401,
AY050309
Ensembl:
ENSMUSG00000026602
KO:
mmu:170484
|
Nucleutide sequences |
EMBL-CDS:
CAC44636.1,
BAC35128.1,
AAL06146.1,
AAH67401.1,
ACN67095.1
Ensembl_TRS:
ENSMUST00000027896
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027896
RefSeq:
XP_011237067.1,
XP_006496747.1,
NP_569723.1,
XP_006496746.1
|
Others |
UniRef100:
UniRef100_Q91X05
UniRef90:
UniRef90_Q91X05
UniRef50:
UniRef50_Q9NP85
UniGene:
Mm.289099
CCDS:
CCDS15391.1
|
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