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17035 Lxn

17035

Lxn

latexin

protein-coding

Mus musculus

基因描述

Type Description
Definition latexin

研究结论

Date Results Publications
2020-12-12 13:22:00 Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-kappaB pathway. 32555320
2017-05-20 11:55:00 By using an Lxn knockout mouse model, this study found that Lxn inactivation in vivo led to the physiological expansion of the entire hematopoietic hierarchy. Loss of Lxn enhanced the competitive repopulation capacity and survival of hematopoietic stem cells in a cell-intrinsic manner. 28330618
2015-06-20 11:08:00 Rps3 knockdown increased the radiation sensitivity of FDC-P1, confirming that the mechanism of action of Lxn is mediated by Rps3 pathway. 25341047
2013-03-02 10:50:00 These results are consistent with a tumor suppressor role for latexin. 23028717
2012-04-28 10:33:00 Latexin is preferentially expressed in hematopoietic stem cells, and is co-localized with the molecules responsible for the interaction of hematopoietic stem cells with a bone marrow niche. 21567403

名称对应

Type IDs
Gene
UniProtKB-ID: LXN_MOUSE, Q14BZ3_MOUSE
UniprotKB: P70202, Q14BZ3
UniParc: UPI0000022CBB
EMBL: BC115521, D88769, AK032170, AK149981, BC115522
Ensembl: ENSMUSG00000047557
KO: mmu:17035
Nucleutide sequences
EMBL-CDS: BAC27739.1, BAA13700.1, BAE29211.1, AAI15523.1, AAI15522.1
Ensembl_TRS: ENSMUST00000058981
Protein sequencees
Ensembl_PRO: ENSMUSP00000060732
RefSeq: NP_058033.2
Others
UniRef100: UniRef100_P70202
UniRef90: UniRef90_P70202
UniRef50: UniRef50_Q9BS40
UniGene: Mm.2632
CCDS: CCDS17397.1

全选

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研究热度

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