Type | Description |
---|---|
Definition | latexin |
Date | Results | Publications |
---|---|---|
2020-12-12 13:22:00 | Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-kappaB pathway. | 32555320 |
2017-05-20 11:55:00 | By using an Lxn knockout mouse model, this study found that Lxn inactivation in vivo led to the physiological expansion of the entire hematopoietic hierarchy. Loss of Lxn enhanced the competitive repopulation capacity and survival of hematopoietic stem cells in a cell-intrinsic manner. | 28330618 |
2015-06-20 11:08:00 | Rps3 knockdown increased the radiation sensitivity of FDC-P1, confirming that the mechanism of action of Lxn is mediated by Rps3 pathway. | 25341047 |
2013-03-02 10:50:00 | These results are consistent with a tumor suppressor role for latexin. | 23028717 |
2012-04-28 10:33:00 | Latexin is preferentially expressed in hematopoietic stem cells, and is co-localized with the molecules responsible for the interaction of hematopoietic stem cells with a bone marrow niche. | 21567403 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
LXN_MOUSE,
Q14BZ3_MOUSE
UniprotKB:
P70202,
Q14BZ3
UniParc:
UPI0000022CBB
EMBL:
BC115521,
D88769,
AK032170,
AK149981,
BC115522
Ensembl:
ENSMUSG00000047557
KO:
mmu:17035
|
Nucleutide sequences |
EMBL-CDS:
BAC27739.1,
BAA13700.1,
BAE29211.1,
AAI15523.1,
AAI15522.1
Ensembl_TRS:
ENSMUST00000058981
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000060732
RefSeq:
NP_058033.2
|
Others |
UniRef100:
UniRef100_P70202
UniRef90:
UniRef90_P70202
UniRef50:
UniRef50_Q9BS40
UniGene:
Mm.2632
CCDS:
CCDS17397.1
|
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