| Type | Description |
|---|---|
| Definition | leukotriene A4 hydrolase |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 11:01:00 | Gliotoxin suppresses the biosynthesis of the potent neutrophil chemoattractant LTB4 by direct interference with LTA4H thereby impairing neutrophil functions in invasive aspergillosis. | 30745237 |
| 2019-07-06 12:59:00 | LTA4H is the major Pro-Gly-Pro degrading enzyme. | 29051536 |
| 2017-10-07 10:11:00 | These findings indicate that LTA4H is critical for skin carcinogenesis and is an important mediator of cell cycle and the data begin to clarify the mechanisms of LTA4H's role in cancer development. | 28575166 |
| 2016-05-07 11:27:00 | There is a critical role for the secondary anti-inflammatory activity of LTA4H in acute pulmonary infection. | 26400771 |
| 2014-07-05 11:49:00 | CS exposure promotes the development of CS-induced emphysema by suppressing the enzymatic activities of the LTA4H aminopeptidase in lung tissues and accumulating PGP and neutrophils in the airspaces. | 24771855 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LKHA4_MOUSE
UniprotKB:
P24527
UniParc:
UPI0000021436
EMBL:
AK134931,
M63848,
BC021417
Ensembl:
ENSMUSG00000015889
KO:
mmu:16993
|
| Nucleutide sequences |
EMBL-CDS:
AAB59675.1,
AAH21417.1,
BAE22342.1
Ensembl_TRS:
ENSMUST00000016033
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000016033
RefSeq:
NP_001300826.1,
NP_032543.2
|
| Others |
UniRef100:
UniRef100_P24527
UniRef90:
UniRef90_P09960-4
UniRef50:
UniRef50_P09960-4
UniGene:
Mm.271071
CCDS:
CCDS24125.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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