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16975 Lrp8

16975

Lrp8

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

研究结论

Date Results Publications
2021-02-27 13:54:00 Angiotensin II Infusion Leads to Aortic Dissection in LRP8 Deficient Mice. 32664652
2018-11-10 11:21:00 The data of the present study demonstrated that the PCSK9 shRNAmediated antiapoptotic effect induced by MCAO in hyperlipidemic mice is associated with ApoER2 downregulation, which may be a potential new therapy for stroke treatment in patients with hyperlipidemia. 30066942
2018-08-04 11:03:00 Stage-specific labeling of newborn Apoer2-deficient neurons revealed that the neurons ectopically invaded the marginal zone and that neuronal migration of both early- and late-born neurons was disrupted in the intermediate zone in the Apoer2 KO mice. Rescue experiments showed that ApoER2 functions both in cell-autonomous and noncell-autonomous manners. 27909010
2018-05-26 11:11:00 GRIP1 binds to apoER2 and EphrinB2 to induce activity-dependent AMPA receptor insertion at the synapse. 28978486
2018-01-13 14:22:00 A1-A1, which is a soluble analog of ApoER2 that binds pathological beta2GPI/anti-beta2GPI complexes, has a positive impact on hemodynamics in lupus-prone mice with spontaneous anti-beta2GPI antibodies and hypertension 26990752

名称对应

Type IDs
Synonymous 4932703M08Rik, AA921429, AI848122, ApoER2, Lr8b
Gene
UniProtKB-ID: A0A571BE60_MOUSE, F6YZZ8_MOUSE, B1AXJ4_MOUSE, B1AXJ5_MOUSE
UniprotKB: A0A571BE60, F6YZZ8, B1AXJ4, B1AXJ5
UniParc: UPI0005AB9947, UPI000035B1CB, UPI000059E040, UPI000024DE48
EMBL: AL807828, AL611936
Ensembl: ENSMUSG00000028613
KO: mmu:16975
Nucleutide sequences
Ensembl_TRS: ENSMUST00000238584, ENSMUST00000106731, ENSMUST00000030356, ENSMUST00000106733
Protein sequencees
Ensembl_PRO: ENSMUSP00000158610, ENSMUSP00000102342, ENSMUSP00000030356, ENSMUSP00000102344
RefSeq: XP_036019648.1, NP_001355980.1, XP_036019661.1, NP_001074395.1, XP_036019663.1, XP_011238763.1, XP_036019659.1, XP_036019647.1, XP_030109139.1, XP_036019656.1, XP_036019646.1, XP_036019651.1, XP_036019652.1, XP_036019657.1, XP_036019655.1, XP_030109138.1, XP_030109141.1, XP_036019654.1, XP_011238768.1, XP_036019664.1, XP_030109143.1, XP_036019653.1, NP_001355981.1, XP_036019662.1, XP_011238761.1, XP_036019658.1, XP_011238760.1, XP_011238765.1, NP_001355983.1, XP_036019649.1, XP_030109137.1, XP_011238757.1, XP_017175492.1, XP_011238758.1, XP_036019660.1, XP_036019650.1, XP_011238766.1, XP_011238762.1, XP_030109144.1, XP_011238767.1, NP_444303.2, XP_030109142.1, XP_011238769.1, XP_011238764.1, NP_001355982.1, XP_011238756.1
Others
UniRef100: UniRef100_F6YZZ8, UniRef100_B1AXJ4, UniRef100_A0A571BE60, UniRef100_B1AXJ5
UniRef90: UniRef90_Q924X6-2, UniRef90_A0A571BE60, UniRef90_B1AXJ4
UniRef50: UniRef50_Q99087, UniRef50_Q924X6
UniGene: Mm.442134

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