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16949 Loxl1

16949

Loxl1

lysyl oxidase-like 1

protein-coding

Mus musculus

基因描述

Type Description
Definition lysyl oxidase-like 1

研究结论

Date Results Publications
2021-04-03 13:32:00 Dill Extract Induces Elastic Fiber Neosynthesis and Functional Improvement in the Ascending Aorta of Aged Mice with Reversal of Age-Dependent Cardiac Hypertrophy and Involvement of Lysyl Oxidase-Like-1. 31979322
2021-03-06 13:33:00 Integral role for lysyl oxidase-like-1 in conventional outflow tissue function and behavior. 32623782
2019-07-13 11:04:00 LOXL1-deficient mice are protected from experimental lung fibrosis induced by overexpression of TGF-beta1 using adenoviral (Ad) gene transfer (AdTGF-beta1) by preventing accumulation of insoluble cross-linked collagen in the lungs, and therefore limiting lung stiffness. 29115860
2019-05-25 12:09:00 the copper transporter ATP7A is necessary for the activity of LOX and LOXL enzymes. Silencing of ATP7A inhibited LOX activity in the 4T1 mammary carcinoma cell line. 30890638
2019-04-20 12:15:00 We conclude that LOXL1 has a strong tendency to aggregate in the rER when expressed in vivo at high amounts. A similar scenario, involving intracellular aggregation of LOXL1 and secretion of LOXL1 aggregates into the extracellular space, may be involved in the early pathogenetic events in eyes of PEX patients. 30399364

名称对应

Type IDs
Synonymous Loxl
Gene
UniProtKB-ID: LOXL1_MOUSE, A0A0R4J0Q4_MOUSE
UniprotKB: P97873, A0A0R4J0Q4
UniParc: UPI0000001ACA, UPI00000298BB
EMBL: AH006767, AF357006, BC003973, AC160976, U79144, BC037999
Ensembl: ENSMUSG00000032334
KO: mmu:16949
Nucleutide sequences
EMBL-CDS: AAH37999.1, AAB86802.1, AAH03973.1, AAK97375.1, AAC53067.1
Ensembl_TRS: ENSMUST00000061799
Protein sequencees
Ensembl_PRO: ENSMUSP00000057406
RefSeq: NP_034859.2
Others
UniRef100: UniRef100_P97873, UniRef100_A0A0R4J0Q4
UniRef90: UniRef90_P97873
UniRef50: UniRef50_Q08397
UniGene: Mm.250492
CCDS: CCDS52813.1

全选

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