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16912 Psmb9

16912

Psmb9

proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)

protein-coding

Mus musculus

基因描述

Type Description
Definition proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)

研究结论

Date Results Publications
2019-07-20 13:01:00 co-inhibition of LMP2 and LMP7 appears to be synergistic and advantageous for the treatment of autoimmune diseases. 30279279
2019-07-06 12:02:00 LMP2 is crucial for lymphocyte development and survival in the periphery. LMP2-deficient lymphocytes show impaired degradation of key BH3-only proteins, resulting in elevated levels of pro-apoptotic BIM and increased cell death. 29738610
2016-04-30 12:07:00 Although treatment with IFN-gamma strongly induced the activation of as a transcriptional activator, its target molecule, IRF1, was not clearly produced in Lmp2-deficient uterine smooth muscle cells. 26254356
2014-06-28 13:52:00 down-regulation of IL-33 protein levels by IFN-gamma in pulmonary fibroblasts and in the lungs in vivo occurs through and non-canonical use of the LMP2 proteasome 24619410
2014-02-15 10:45:00 Data show that knockdown of i-proteasome catalytic subunit PSMB9 by short hairpin RNA (shRNA) decreased the expression of both PSMB9 and PSMB8 without affecting other catalytic subunits of the proteasome. 24164898

名称对应

Type IDs
Synonymous Lmp-2, Lmp2
Gene
UniProtKB-ID: PSB9_MOUSE, A0A0R4J256_MOUSE
UniprotKB: P28076, A0A0R4J256
UniParc: UPI0000027C5C, UPI0000022305
EMBL: L11613, S59862, AF027865, AF100956, S58203, D43620, D14566, D44457, D44462, U22919, D44460, U22920, U35323, AK008429, U22447, U22448, D44458, D44461, D44454, CR974422
Ensembl: ENSMUSG00000096727
KO: mmu:16912
Nucleutide sequences
EMBL-CDS: AAA75306.1, AAC69911.1, AAP13903.1, AAA75307.1, BAB25664.1, BAA22581.1, BAA22575.1, BAA22579.1, AAA75304.1, AAA39439.1, BAA22578.1, BAA22583.1, AAA75305.1, AAB81528.1, BAA40680.1, AAB20105.1, BAA22582.1, BAA19855.1, AAA98932.1
Ensembl_TRS: ENSMUST00000174576
Protein sequencees
Ensembl_PRO: ENSMUSP00000133499
RefSeq: NP_038613.1, XP_006523793.1
Others
UniRef100: UniRef100_P28076, UniRef100_A0A0R4J256
UniRef90: UniRef90_P28076
UniRef50: UniRef50_P28076
UniGene: Mm.390983
CCDS: CCDS28642.1

全选

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