Type | Description |
---|---|
Definition | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) |
Date | Results | Publications |
---|---|---|
2019-07-20 13:01:00 | co-inhibition of LMP2 and LMP7 appears to be synergistic and advantageous for the treatment of autoimmune diseases. | 30279279 |
2019-07-06 12:02:00 | LMP2 is crucial for lymphocyte development and survival in the periphery. LMP2-deficient lymphocytes show impaired degradation of key BH3-only proteins, resulting in elevated levels of pro-apoptotic BIM and increased cell death. | 29738610 |
2016-04-30 12:07:00 | Although treatment with IFN-gamma strongly induced the activation of as a transcriptional activator, its target molecule, IRF1, was not clearly produced in Lmp2-deficient uterine smooth muscle cells. | 26254356 |
2014-06-28 13:52:00 | down-regulation of IL-33 protein levels by IFN-gamma in pulmonary fibroblasts and in the lungs in vivo occurs through and non-canonical use of the LMP2 proteasome | 24619410 |
2014-02-15 10:45:00 | Data show that knockdown of i-proteasome catalytic subunit PSMB9 by short hairpin RNA (shRNA) decreased the expression of both PSMB9 and PSMB8 without affecting other catalytic subunits of the proteasome. | 24164898 |
Type | IDs |
---|---|
Synonymous | Lmp-2, Lmp2 |
Gene |
UniProtKB-ID:
PSB9_MOUSE,
A0A0R4J256_MOUSE
UniprotKB:
P28076,
A0A0R4J256
UniParc:
UPI0000027C5C,
UPI0000022305
EMBL:
L11613,
S59862,
AF027865,
AF100956,
S58203,
D43620,
D14566,
D44457,
D44462,
U22919,
D44460,
U22920,
U35323,
AK008429,
U22447,
U22448,
D44458,
D44461,
D44454,
CR974422
Ensembl:
ENSMUSG00000096727
KO:
mmu:16912
|
Nucleutide sequences |
EMBL-CDS:
AAA75306.1,
AAC69911.1,
AAP13903.1,
AAA75307.1,
BAB25664.1,
BAA22581.1,
BAA22575.1,
BAA22579.1,
AAA75304.1,
AAA39439.1,
BAA22578.1,
BAA22583.1,
AAA75305.1,
AAB81528.1,
BAA40680.1,
AAB20105.1,
BAA22582.1,
BAA19855.1,
AAA98932.1
Ensembl_TRS:
ENSMUST00000174576
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000133499
RefSeq:
NP_038613.1,
XP_006523793.1
|
Others |
UniRef100:
UniRef100_P28076,
UniRef100_A0A0R4J256
UniRef90:
UniRef90_P28076
UniRef50:
UniRef50_P28076
UniGene:
Mm.390983
CCDS:
CCDS28642.1
|
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Refseq |
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