| Type | Description |
|---|---|
| Definition | LLGL1 scribble cell polarity complex component |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | Bleomycin induced apical-basal polarity loss in alveolar epithelial cell contributes to experimental pulmonary fibrosis. | 32971116 |
| 2020-03-14 10:54:00 | Lgl1-/- mice exhibited reduced size of the hippocampus and impaired cognitive performance. | 31415124 |
| 2019-06-22 10:34:00 | Study concludes that lethal giant larvae 1 is essential for radial glial cell development and neural migration during cerebral cortex development. | 30597194 |
| 2018-12-22 11:08:00 | Study showed that Lgl bound with and PAR-6B competing against PAR-3A in PAR complex which resulted in pleural mesothelial cell (PMCs) polarity loss, and Lgl1 knockdown maintained the PMC polarity and attenuated pleural fibrosis. | 29842893 |
| 2018-12-22 10:29:00 | Data establish Lgl1 as a suppressor of gliomagenesis and positive regulator of asymmetric division and differentiation in the healthy and demyelinated murine brain. | 30131568 |
| Type | IDs |
|---|---|
| Synonymous | AI325176, Lgl1, Llglh, Mgl1 |
| Gene |
UniProtKB-ID:
L2GL1_MOUSE,
A0A0R4J0S4_MOUSE
UniprotKB:
Q80Y17,
A0A0R4J0S4
UniParc:
UPI00001B5CEB,
UPI000018FE2E
EMBL:
AK159412,
BC055399,
AK084386,
D16141,
AL596215,
BC050913
Ensembl:
ENSMUSG00000020536
KO:
mmu:16897
|
| Nucleutide sequences |
EMBL-CDS:
AAH55399.1,
BAE35062.1,
BAC39171.1,
AAH50913.1,
BAA03712.1
Ensembl_TRS:
ENSMUST00000108719,
ENSMUST00000052346
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104359,
ENSMUSP00000060749
RefSeq:
NP_001152877.1,
XP_036012256.1,
NP_001365765.1,
NP_032528.1,
XP_030101473.1,
XP_036012257.1,
NP_001365766.1,
NP_001152876.1
|
| Others |
UniRef100:
UniRef100_Q80Y17
UniRef90:
UniRef90_Q8K4K5
UniRef50:
UniRef50_Q15334
UniGene:
Mm.285453
CCDS:
CCDS48813.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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