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16881 Lig1

16881

Lig1

ligase I, DNA, ATP-dependent

protein-coding

Mus musculus

基因描述

Type Description
Definition ligase I, DNA, ATP-dependent

研究结论

Date Results Publications
2017-01-14 11:43:00 Increased presynaptic glutamate release is a key early event resulting from Lgi1-deficiency, which likely contributes to epileptogenesis. 26878798
2015-01-03 11:42:00 Lig1 is not absolutely required for cellular DNA replication and repair in Lig1-null cell line. 24726358
2011-08-27 10:15:00 LigI has a highly specific role in CTG repeat maintenance in the maternal germline, involved in mediating CTG expansions and in the avoidance of maternal CTG contractions. 21378394
2010-01-21 00:00:00 DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability. 11896201

名称对应

Type IDs
Synonymous AL033288, LigI
Gene
UniProtKB-ID: DNLI1_MOUSE, Q3U4X8_MOUSE, Q3TSU8_MOUSE, Q8R055_MOUSE
UniprotKB: P37913, Q3U4X8, Q3TSU8, Q8R055
UniParc: UPI00000299F2, UPI00005B1DAE, UPI00000E730E, UPI0000563D34
EMBL: AC161792, AK153993, BC028287, BC138541, BC138542, AK161793, U04674, U19604
Ensembl: ENSMUSG00000056394
KO: mmu:16881
Nucleutide sequences
EMBL-CDS: AAA70403.1, AAB60500.1, BAE32302.1, AAI38543.1, AAI38542.1, BAE36577.1, AAH28287.1
Ensembl_TRS: ENSMUST00000165964, ENSMUST00000177588, ENSMUST00000098814
Protein sequencees
Ensembl_PRO: ENSMUSP00000136972, ENSMUSP00000096411, ENSMUSP00000126525
RefSeq: NP_001076657.2, NP_001186239.2, NP_034845.3
Others
UniRef100: UniRef100_Q3U4X8, UniRef100_Q3TSU8, UniRef100_P37913
UniRef90: UniRef90_P37913, UniRef90_Q3TSU8
UniRef50: UniRef50_P18858-2, UniRef50_A0A6I8R933
UniGene: Mm.288179, Mm.421129

全选

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