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16880 Lifr

16880

Lifr

LIF receptor alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition LIF receptor alpha

研究结论

Date Results Publications
2020-12-12 13:23:00 Immunization against leukemia inhibitory factor and its receptor suppresses tumor formation of breast cancer initiating cells in BALB/c mouse. 32651426
2019-10-19 10:53:00 Sertoli cell LIFR ablation results in a degenerative phenotype, characterised by abnormal germ cell loss, sperm stasis, seminiferous tubule distention and subsequent atrophy of the seminiferous tubules. 30068994
2017-10-21 10:05:00 Authors demonstrate heterozygous novel or rare LIFR mutations in 3.3% of CAKUT patients, and provide evidence that Lifr deficiency and deactivating LIFR mutations cause highly similar anomalies of the urogenital tract in mice and humans. 28334964
2017-09-09 14:26:00 uterine expression of the LIFR is essential for embryo implantation; this further define the components of the LIF signaling pathway necessary for effective implantation. 28368537
2017-05-20 14:49:00 OSM (mOSM) signals mainly via an OSM receptor (OSMR)-gp130 heterodimer and binds with only very low affinity to mLIFR. 27539849

名称对应

Type IDs
Synonymous A230075M04Rik, AW061234, LIF
Gene
UniProtKB-ID: LIFR_MOUSE, Q3UKU5_MOUSE
UniprotKB: P42703, Q3UKU5
UniParc: UPI00005AC482, UPI000002824E, UPI0000001A98
EMBL: BC031929, D17444, S73496, D26177, AK145864, S73495
Ensembl: ENSMUSG00000054263
KO: mmu:16880
Nucleutide sequences
EMBL-CDS: AAH31929.1, BAA04258.1, AAC60697.1, BAA05165.1, AAC60698.1, BAE26706.1
Ensembl_TRS: ENSMUST00000164529, ENSMUST00000227727, ENSMUST00000067190, ENSMUST00000226471, ENSMUST00000226934, ENSMUST00000171588
Protein sequencees
Ensembl_PRO: ENSMUSP00000154181, ENSMUSP00000064551, ENSMUSP00000126137, ENSMUSP00000154750, ENSMUSP00000131434, ENSMUSP00000153968
RefSeq: XP_006520032.1, XP_011243628.1, XP_006520033.1, NP_001106857.1, NP_001345522.1, NP_038612.1, XP_006520034.1
Others
UniRef100: UniRef100_P42703, UniRef100_Q3UKU5
UniRef90: UniRef90_P42703, UniRef90_P42703-2
UniRef50: UniRef50_P42703-2, UniRef50_P42702
UniGene: Mm.149720
CCDS: CCDS49577.1, CCDS27369.1

全选

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