| Type | Description |
|---|---|
| Definition | LIM homeobox protein 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:37:00 | Study in Nf1 knockout mice discovered that loss of Nf1 results in a dose-dependent decrease in Lhx6 expression, the transcription factor necessary to establish somatostatin- and parvalbumin-positive cortical GABAergic interneurons (CINs), which was rescued by the MEK inhibitor SL327, revealing a mechanism whereby a neurofibromin/Ras/MEK pathway regulates a critical CIN developmental milestone. | 32123116 |
| 2020-04-25 10:49:00 | Lhx6 was expressed in retinal ganglion cells and amacrine cells in both the adult and developing mouse retina | 31376504 |
| 2017-09-16 11:19:00 | studies identify Lhx6-positive GABAergic neurons in the ventral zona incerta that promote sleep | 28847002 |
| 2016-05-21 10:57:00 | LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt/beta-catenin signaling pathway. | 26129710 |
| 2016-05-14 12:14:00 | Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2 | 26071365 |
| Type | IDs |
|---|---|
| Synonymous | Lhx6.1 |
| Gene |
UniProtKB-ID:
LHX6_MOUSE,
E9QN32_MOUSE,
H9H9T0_MOUSE
UniprotKB:
Q9R1R0,
E9QN32,
H9H9T0
UniParc:
UPI0000233028,
UPI0000434FA9,
UPI0000216C01,
UPI00001EEF68
EMBL:
AB031040,
AB031039,
AL773525,
AJ000337,
BC065077
Ensembl:
ENSMUSG00000026890
KO:
mmu:16874
|
| Nucleutide sequences |
EMBL-CDS:
AAH65077.1,
BAA83420.1,
BAA83421.1,
CAA04011.1
Ensembl_TRS:
ENSMUST00000112961,
ENSMUST00000112963,
ENSMUST00000112966,
ENSMUST00000148852,
ENSMUST00000112967,
ENSMUST00000112960
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000135693,
ENSMUSP00000108587,
ENSMUSP00000108585,
ENSMUSP00000108590,
ENSMUSP00000108591,
ENSMUSP00000108584
RefSeq:
XP_006497807.1,
NP_032526.2,
NP_001076594.1,
NP_001076595.1,
NP_001342054.1,
NP_001076596.1
|
| Others |
UniRef100:
UniRef100_E9QN32,
UniRef100_Q9R1R0
UniRef90:
UniRef90_Q9R1R0
UniRef50:
UniRef50_Q9R1R0
UniGene:
Mm.12881
CCDS:
CCDS38113.1,
CCDS38111.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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