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16871 Lhx3

16871

Lhx3

LIM homeobox protein 3

protein-coding

Mus musculus

基因描述

Type Description
Definition LIM homeobox protein 3

研究结论

Date Results Publications
2018-02-03 10:44:00 Results show that specific genomic loci associated with Islet-1 (Isl1) , LIM-homeobox 3 (Lhx3), and LMO4 genes recruit the Isl1-Lhx3 complex to activate the transcription of Isl1, Lhx3, and Lmo4. 28451636
2017-11-18 10:07:00 Together, the authors show the antagonistic regulation of the alpha-enhancer activity by Pax6 and the LIM protein complex is necessary for the establishment of an inner retinal circuitry, which controls visual adaptation. 28139974
2017-10-14 13:03:00 conditional deletion of Shh in the anterior hypothalamus results in a fully penetrant phenotype characterised by a complete arrest of (Rathke's pouch) RP development, with lack of Lhx3/Lhx4 expression in RP epithelium. 28807898
2017-07-29 10:07:00 Expression of motor neuron effector genes is maintained by transient enhancers bound by Isl1/Lhx3 in nascent motor neurons and Isl1/Onecut1 in maturing hypaxial motor neurons. 27939581
2016-04-30 12:03:00 All E1 sequences from lamprey to mouse responded equally well to Phox2a and the Isl1-Lhx3 complex. Conversely, E2, the enhancer for limb-innervating motor neurons, was only found in tetrapod animals 26447474

名称对应

Type IDs
Synonymous Lim3, P-LIM, mLIM3, mLim-3
Gene
UniProtKB-ID: LHX3_MOUSE, A2ALD8_MOUSE
UniprotKB: P50481, A2ALD8
UniParc: UPI0000022A5A, UPI000002AD3E
EMBL: L38249, BC150689, L38248, BC132554, L33776, L38857, BC132556
Ensembl: ENSMUSG00000026934
KO: mmu:16871
Nucleutide sequences
EMBL-CDS: AAI50690.1, AAA62369.1, AAA98998.1, AAB64178.1, AAA73902.1, AAI32557.1, AAI32555.1
Ensembl_TRS: ENSMUST00000028302, ENSMUST00000054099
Protein sequencees
Ensembl_PRO: ENSMUSP00000056822, ENSMUSP00000028302
RefSeq: NP_001034742.1, NP_034841.2, XP_011237333.1
Others
UniRef100: UniRef100_P50481, UniRef100_A2ALD8
UniRef90: UniRef90_H0V9C1, UniRef90_P50481
UniRef50: UniRef50_P36200, UniRef50_P50481
UniGene: Mm.386765
CCDS: CCDS38081.1, CCDS71004.1

全选

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