| Type | Description |
|---|---|
| Definition | gasdermin E |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | DFNA5 (GSDME) c.991-15_991-13delTTC: Founder Mutation or Mutational Hotspot? | 32486382 |
| 2020-12-05 12:59:00 | Gasdermine E-Dependent Mitochondrial Pyroptotic Pathway in Dermatomyositis: A Possible Mechanism of Perifascicular Atrophy. | 32296846 |
| 2020-10-10 13:02:00 | Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome. | 31953257 |
| 2020-06-13 12:49:00 | Results found differential methylation in all 22 GSDME CpGs between colorectal cancer (GC) tumor and normal tissues, and in 18 CpGs between the left- and right-sided groups. Although the methylation of 5 distinct probes was a good predictor of gene expression, no association was found between GSDME methylation and its expression. However, a combination of 2 CpGs was found to discriminate between cancer and normal tumor. | 30993897 |
| 2020-05-30 10:48:00 | tumor GSDME acts as a tumor suppressor by activating pyroptosis, enhancing anti-tumor immunity | 32188940 |
| Type | IDs |
|---|---|
| Synonymous | DFNA5, ICERE-1 |
| Gene |
UniProtKB-ID:
GSDME_HUMAN,
A4FVA8_HUMAN,
A0A024RA58_HUMAN
UniprotKB:
O60443,
A4FVA8,
A0A024RA58
UniParc:
UPI000002A7DA,
UPI0000F58A36,
UPI0000169648,
UPI00001291FC
EMBL:
AF131765,
BC125065,
CH471073,
AF075171,
AC003093,
AK314402,
CH236948,
AF007790,
AF073308,
AK094714,
BC125066
Ensembl:
ENSG00000105928
KO:
hsa:1687
|
| Nucleutide sequences |
EMBL-CDS:
AAI25066.1,
BAG37026.1,
AAD20039.1,
AAB83938.1,
BAG52917.1,
EAW93813.1,
EAL24246.1,
AAC69324.1,
AAC39635.2,
AAC69326.1,
AAI25067.1,
EAW93812.1,
EAW93814.1
Gene_ORFName:
hCG_38835
Ensembl_TRS:
ENST00000645220,
ENST00000419307,
ENST00000342947,
ENST00000409970
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000401332,
ENSP00000387119,
ENSP00000494186,
ENSP00000339587
RefSeq:
NP_001120926.1,
XP_016867291.1,
NP_004394.1,
XP_024302438.1,
NP_001120925.1
|
| Others |
UniRef100:
UniRef100_A4FVA8,
UniRef100_O60443
UniRef90:
UniRef90_O60443
UniRef50:
UniRef50_O60443
UniGene:
Hs.520708
CCDS:
CCDS47563.1,
CCDS5389.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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