| Type | Description |
|---|---|
| Definition | DEAD-box helicase 53 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-18 11:27:00 | DDX53 plays a critical role in taxol-resistance by activating autophagy and a potential therapeutic target for the treatment of taxol-resistant cervix cancer. | 30454700 |
| 2018-03-24 11:10:00 | A novel role of DDX53 in regulating cancer stem cell-like properties by binding to SOX-2.DDX53 directly regulates the SOX-2 expression in drug-resistant melanoma cells. | 28535666 |
| 2017-05-20 14:14:00 | DDX53 promotes stem cell-like properties, autophagy, and confers resistance to anti-cancer drugs in breast cancer cells. | 28152297 |
| 2017-03-04 12:03:00 | Results provide evidence that miR-30a forms a positive feedback loop with CAGE to regulate the expression of p53 confering resistance to anti-cancer drugs. | 26912082 |
| 2016-12-31 11:23:00 | miR-217-CAGE feedback loop serves as a target for overcoming resistance to various anti-cancer drugs, including EGFR and HER2 inhibitors. | 26863629 |
| Type | IDs |
|---|---|
| Synonymous | CAGE, CT26 |
| Gene |
UniProtKB-ID:
DDX53_HUMAN
UniprotKB:
Q86TM3
UniParc:
UPI0000199904
EMBL:
BC067878,
BC051703,
AY039237
Ensembl:
ENSG00000184735
KO:
hsa:168400
|
| Nucleutide sequences |
EMBL-CDS:
AAK72102.1,
AAH51703.1,
AAH67878.1
Ensembl_TRS:
ENST00000327968
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368667
RefSeq:
NP_874358.2
|
| Others |
UniRef100:
UniRef100_Q86TM3
UniRef90:
UniRef90_Q86TM3
UniRef50:
UniRef50_Q86TM3
UniGene:
Hs.434416
CCDS:
CCDS35214.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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