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16828 Ldha

16828

Ldha

lactate dehydrogenase A

protein-coding

Mus musculus

基因描述

Type Description
Definition lactate dehydrogenase A

研究结论

Date Results Publications
2019-03-30 10:28:00 the LDHA protein level was remarkably decreased in Ldhc-deficient sperm, indicating that LDHC is required for LDHA expression in the sperm. 30590713
2019-03-09 12:38:00 LDH-A depletion inhibits the formation of metastases and prolongs survival through changes in mammary tumor microenvironment that modulate the immune response. We attribute these effects to diminished HIF-1a activity, vascularization, necrosis formation and immune suppression in immune competent animals. 30248111
2018-08-18 12:05:00 The release of lactate dehydrogenase A (LDHA) from degenerating neurons drives central nervous system (CNS) angiogenesis. 29248508
2017-10-07 12:21:00 Hair follicle stem cells maintain a metabolic state that allows them to remain dormant and yet quickly respond to appropriate proliferative stimuli mediated by LDH-A signaling. 28812580
2017-08-26 13:09:00 Results revealed that beta-arrestin-1 regulates lactate metabolism to contribute to beta2-adrenergic receptor functions in improved memory formation. 27916196

名称对应

Type IDs
Synonymous Ldh1, Ldhm, l7R2
Gene
UniProtKB-ID: LDHA_MOUSE, Q564E2_MOUSE, A0A1B0GSX0_MOUSE
UniprotKB: P06151, Q564E2, A0A1B0GSX0
UniParc: UPI0000D77B1E, UPI00000041D9
EMBL: X02522, U13687, X03753, X02521, BC094428, Y00309, M17516, AK168920, X02524, BC094019, X02525, AK170386, AK167789, AC090123, AK089929, X02520, AK150156, X02526, X02523
Ensembl: ENSMUSG00000063229
KO: mmu:16828
Nucleutide sequences
EMBL-CDS: CAA27387.1, AAA39424.1, CAA26360.1, AAA21466.1, CAA68410.1, BAE41760.1, AAH94019.1, BAE39819.1, AAH94428.1, BAC41000.1, BAE29347.1, BAE40733.1
Ensembl_TRS: ENSMUST00000005051, ENSMUST00000048209, ENSMUST00000209984
Protein sequencees
Ensembl_PRO: ENSMUSP00000103267, ENSMUSP00000036386, ENSMUSP00000148107
RefSeq: NP_001129541.2, XP_030098036.1, NP_034829.1
Others
UniRef100: UniRef100_P06151
UniRef90: UniRef90_P04642
UniRef50: UniRef50_P04642
UniGene: Mm.29324
CCDS: CCDS21289.1

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