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16825 Ldb1

16825

Ldb1

LIM domain binding 1

protein-coding

Mus musculus

基因描述

Type Description
Definition LIM domain binding 1

研究结论

Date Results Publications
2021-02-20 13:29:00 Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia. 32181817
2021-01-02 12:52:00 An evolutionarily conserved Lhx2-Ldb1 interaction regulates the acquisition of hippocampal cell fate and regional identity. 32994168
2019-10-12 10:46:00 We demonstrate that RUNX1 induction moves FLI1 from distal ETS/GATA sites to RUNX1/ETS sites and recruits the basal transcription factors CDK9, BRD4, the Mediator complex and the looping factor LDB1 29991720
2019-07-06 12:59:00 Greek-island-bound transcription factor LHX2 and adaptor protein LDB1 regulate the assembly and maintenance of olfactory receptor compartments, Greek island hubs and olfactory receptor transcription, providing mechanistic insights into and functional support for the role of trans interactions in gene expression 30626972
2019-06-08 12:02:00 Study identifies Pax3 interaction with members of the chromatin looping complex, including the LIM-domain binding protein 1 (Ldb1) and demonstrates that Ldb1 is recruited to a subset of Pax3-bound elements characterized by increased levels of H3K4me1 deposition. Reduced Ldb1 expression impairs Pax3-dependent myogenic specification both in vitro and in vivo. 31127120

名称对应

Type IDs
Synonymous CLIM2, NLI
Gene
UniProtKB-ID: LDB1_MOUSE
UniprotKB: P70662
UniParc: UPI000000193C, UPI0000000121, UPI0000D83535
EMBL: BC013624, AF024524, AB250383, U69270, U89488, AF030333, U70375
Ensembl: ENSMUSG00000025223
KO: mmu:16825
Nucleutide sequences
EMBL-CDS: AAB94131.1, AAB96885.1, AAH13624.1, AAC40064.1, AAC52933.1, AAC52887.1, BAE95401.1
Ensembl_TRS: ENSMUST00000026252, ENSMUST00000156585, ENSMUST00000185355, ENSMUST00000056931, ENSMUST00000137771
Protein sequencees
Ensembl_PRO: ENSMUSP00000053680, ENSMUSP00000139562, ENSMUSP00000114667, ENSMUSP00000026252, ENSMUSP00000118546
RefSeq: XP_006526786.3, NP_001347265.1, NP_001106879.1, XP_036017346.1, XP_030106620.1, XP_030106619.1, NP_034827.1
Others
UniRef100: UniRef100_P70662
UniRef90: UniRef90_P70662
UniRef50: UniRef50_P70662
UniGene: Mm.327442
CCDS: CCDS29870.1, CCDS50455.1

全选

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