| Type | Description |
|---|---|
| Definition | dishevelled binding antagonist of beta catenin 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:38:00 | Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa. | 32454406 |
| 2019-08-10 10:43:00 | An association was found of DACT2 promoter methylation with advanced tumor stages. This gene has been suggested as a potential biomarker, however, more investigation is required to validate this function. | 29745077 |
| 2019-07-20 13:04:00 | Studies suggested that DACT2 expression in nasopharyngeal carcinoma cells is restored by TET1 which demethylates its promotor region. | 30075814 |
| 2019-03-02 10:57:00 | Results demonstrate that DACT2 is frequently inactivated epigenetically by CpG methylation in nasopharyngeal carcinoma (NPC), while it inhibits NPC cell proliferation and metastasis via suppressing beta-catenin/Cdc25c signaling. These findings suggest that DACT2 promoter methylation is a potential epigenetic biomarker for the detection of NPC. | 30359298 |
| 2019-01-26 10:54:00 | Our findings provide a novel DACT2 demethylating stimulator to verify and expand previously established link between DACT2 and colorectal cancer (CRC), suggesting DACT2 demethylation is strongly correlated with CRC prognosis. | 29199082 |
| Type | IDs |
|---|---|
| Synonymous | C6orf116, DAPPER2, DPR2, bA503C24.7 |
| Gene |
UniProtKB-ID:
DACT2_HUMAN
UniprotKB:
Q5SW24
UniParc:
UPI000013E3B2,
UPI00001D8145,
UPI000153D925,
UPI0000D6151B
EMBL:
BC111764,
BC092498,
AF318336,
AL606970,
BC111790
Ensembl:
ENSG00000164488
KO:
hsa:168002
|
| Nucleutide sequences |
EMBL-CDS:
AAI11791.1,
AAH92498.1,
AAL55843.1,
AAI11765.1
Gene_ORFName:
PP13671
Ensembl_TRS:
ENST00000366795,
ENST00000607983,
ENST00000610183,
ENST00000366796
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355761,
ENSP00000355760,
ENSP00000476434,
ENSP00000476573
RefSeq:
NP_001273279.1,
NP_999627.2,
XP_011533809.1,
NP_001273280.1
|
| Others |
UniRef100:
UniRef100_Q5SW24
UniRef90:
UniRef90_Q5SW24
UniRef50:
UniRef50_Q7TN08
UniGene:
Hs.673059
CCDS:
CCDS75554.1,
CCDS69241.1,
CCDS47519.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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