| Type | Description |
|---|---|
| Definition | large tumor suppressor |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:27:00 | Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate. | 32243503 |
| 2020-10-10 13:00:00 | YAP Mediates Hair Cell Regeneration in Balance Organs of Chickens, But LATS Kinases Suppress Its Activity in Mice. | 32341094 |
| 2020-06-27 11:45:00 | Data show that conditional deletion of the key Hippo kinases Lats1 and Lats2 in mouse Mullerian duct mesenchyme cells caused them to adopt the myofibroblast cell fate, resulting in profound reproductive tract developmental defects and sterility. | 31575647 |
| 2020-06-06 11:48:00 | Inactivation of Lats1/2 in granulosa cells either in vitro or in vivo resulted in a loss of granulosa cell morphology, function, and gene expression. Mutant cells further underwent changes in structure and gene expression suggestive of epithelial-to-mesenchymal transition and transdifferentiation into multiple lineages. | 31268774 |
| 2020-04-18 12:36:00 | Lats1 and Lats2 suppress mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. | 32015438 |
| Type | IDs |
|---|---|
| Synonymous | AW208599 |
| Gene |
UniProtKB-ID:
LATS1_MOUSE
UniprotKB:
Q8BYR2
UniParc:
UPI00006062EE
EMBL:
AF104414,
BC158123,
BC158092,
AK038612
Ensembl:
ENSMUSG00000116422,
ENSMUSG00000040021
KO:
mmu:16798
|
| Nucleutide sequences |
EMBL-CDS:
AAI58093.1,
AAD16883.1,
AAI58124.1,
BAC30063.1
Ensembl_TRS:
ENSMUST00000229932,
ENSMUST00000165952,
ENSMUST00000230889,
ENSMUST00000217931,
ENSMUST00000229089,
ENSMUST00000040043
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041915,
ENSMUSP00000151533,
ENSMUSP00000155578,
ENSMUSP00000132078,
ENSMUSP00000155011,
ENSMUSP00000155296
RefSeq:
NP_034820.1
|
| Others |
UniRef100:
UniRef100_Q8BYR2
UniRef90:
UniRef90_Q8BYR2
UniRef50:
UniRef50_O95835
UniGene:
Mm.34083
CCDS:
CCDS48494.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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