| Type | Description |
|---|---|
| Definition | LARGE xylosyl- and glucuronyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:30:00 | POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan. | 32975514 |
| 2018-09-08 11:54:00 | These findings indicate that the fine-tuning of AMPA-R trafficking by LARGE at the Golgi is critical for hippocampus-dependent memory in the brain. | 29915039 |
| 2017-08-05 10:45:00 | data suggest LARGE overexpression may only be deleterious under a forced regenerative context, such as that resulting from a reduction in FKRP: in the absence of such a defect we show that systemic expression of LARGE can indeed act therapeutically, and that even dramatic LARGE overexpression is well-tolerated in heart and skeletal muscle | 27467128 |
| 2016-04-16 10:16:00 | A glucuronic acid beta1,4-xylose disaccharide synthesized by B4GAT1 acts as an acceptor primer that can be elongated by LARGE with the ligand-binding heteropolysaccharide. | 25279699 |
| 2015-09-28 09:21:00 | MBP1 inhibits Ab fibril formation in vitro and demonstrate the ability of MBP1 to reduce Ab pathology and improve behavioral performance. | 25457550 |
| Type | IDs |
|---|---|
| Synonymous | BPFD#36, Gyltl1a, Large, Mbp-1, Mbp1, enr, fg, froggy, myd |
| Gene |
UniProtKB-ID:
LARG1_MOUSE,
Q059X9_MOUSE
UniprotKB:
Q9Z1M7,
Q059X9
UniParc:
UPI0000020DF2
EMBL:
BC125487,
BC100399,
AK122328,
BC125489,
BC061506,
AJ006278
Ensembl:
ENSMUSG00000004383
KO:
mmu:16795
|
| Nucleutide sequences |
EMBL-CDS:
CAA06945.1,
BAC65610.1,
AAH61506.1,
AAI00400.1,
AAI25490.1,
AAI25488.1
Ensembl_TRS:
ENSMUST00000004497,
ENSMUST00000119826,
ENSMUST00000212459
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112617,
ENSMUSP00000148336,
ENSMUSP00000004497
RefSeq:
NP_034817.1,
NP_001304320.1,
XP_030099172.1
|
| Others |
UniRef100:
UniRef100_Q9Z1M7
UniRef90:
UniRef90_O95461
UniRef50:
UniRef50_O95461
UniGene:
Mm.324371
CCDS:
CCDS22420.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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