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16782 Lamc2

16782

Lamc2

laminin, gamma 2

protein-coding

Mus musculus

基因描述

Type Description
Definition laminin, gamma 2

研究结论

Date Results Publications
2019-03-09 11:28:00 Study show that integrin alpha9beta1 antagonizes both alpha3beta1-dependent mTLD/BMP-1 expression and basement membrane (BM) assembly/maturation. These findings indicate a complex interplay between these two integrins whereby alpha3beta1 promotes, and coordinately, alpha9beta1 inhibits mTLD/BMP-1 production and laminin-gamma2 processing to effect timely BM assembly and maturation during wound healing. 28923241
2016-05-07 10:21:00 Data suggest that LAMC2 promotes metastasis in lung adenocarcinoma via EMT and may be a potential therapeutic target. 25591736
2011-08-27 10:15:00 Periostin was associated with laminin gamma2, and this association enhanced the proteolytic cleavage of the laminin gamma2 long form to produce its short form. 21490918
2010-07-05 11:39:00 mutant mice develop a progressive blistering disease validated at the gross and microscopic levels to closely resemble generalized non-Herlitz junctional epidermolysis bullosa 20336083
2010-01-21 00:00:00 Thymosin beta(4) stimulates Lamc2 production independent of TGF-beta. 14729067

名称对应

Type IDs
Synonymous AA589349
Gene
UniProtKB-ID: G5E874_MOUSE
UniprotKB: G5E874
UniParc: UPI0000192EF8
EMBL: AC159966, AC099735
Ensembl: ENSMUSG00000026479
KO: mmu:16782
Nucleutide sequences
Ensembl_TRS: ENSMUST00000027753, ENSMUST00000185356
Protein sequencees
Ensembl_PRO: ENSMUSP00000140514, ENSMUSP00000027753
RefSeq: XP_011246228.1, XP_011246229.1, NP_032511.3
Others
UniRef100: UniRef100_G5E874
UniRef90: UniRef90_G5E874
UniRef50: UniRef50_Q13753
UniGene: Mm.329272

全选

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研究热度

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