| Type | Description |
|---|---|
| Definition | AF4/FMR2 family, member 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-07 12:07:00 | AFF3 is associated with the Kruppel-like zinc finger protein ZFP281 in embryonic stem (ES) cells. ZFP281 recruits AFF3 to the Meg3 enhancer within the imprinted Dlk1-Dio3 locus, thus regulating the allele-specific expression of the Meg3 polycistron. | 28180295 |
| 2015-11-07 11:09:00 | The neuronal migration deficit caused by loss of Laf4 can be partially rescued by Mdga2 over-expression, revealing an important functional relationship between these genes in a mouse model of intellectual disability. | 25162227 |
| 2010-01-21 00:00:00 | Alternatively spliced forms encode several forms of putative protein with potentially different transactivation functions. | 12079280 |
| Type | IDs |
|---|---|
| Synonymous | 3222402O04Rik, A730046J16, LAF-4, Laf4 |
| Gene |
UniProtKB-ID:
D3YYI6_MOUSE
UniprotKB:
D3YYI6
UniParc:
UPI0000F2205C
EMBL:
AC117789,
AC122026,
AC138386,
AC132381
Ensembl:
ENSMUSG00000037138
KO:
mmu:16764
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000095027
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000092637
RefSeq:
XP_011236745.1,
XP_011236749.1,
XP_011236746.1,
XP_036018228.1,
NP_001277743.1,
XP_030107416.1,
XP_011236748.1,
XP_006495800.1
|
| Others |
UniRef100:
UniRef100_D3YYI6
UniRef90:
UniRef90_P51827
UniRef50:
UniRef50_P51827
UniGene:
Mm.336679
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28180295 |
A permissive chromatin state regulated by ZFP281-AFF3 in controlling the imprinted Meg3 polycistron. Nucleic Acids Res. Yan Wang , Yang Shen , Qian Dai , Qian Yang , Yue Zhang , Xin Wang , Wei Xie , Zhuojuan Luo , Chengqi Lin |
2017-02-17 | - |
| 24952961 |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron Carol L Thompson , Lydia Ng , Vilas Menon , Salvador Martinez , Chang-Kyu Lee , Katie Glattfelder , Susan M Sunkin , Alex Henry , Christopher Lau , Chinh Dang , Raquel Garcia-Lopez , Almudena Martinez-Ferre , Ana Pombero , John L R Rubenstein , Wayne B Wakeman , John Hohmann , Nick Dee , Andrew J Sodt , Rob Young , Kimberly Smith , Thuc-Nghi Nguyen , Jolene Kidney , Leonard Kuan , Andreas Jeromin , Ajamete Kaykas , Jeremy Miller , Damon Page , Geri Orta , Amy Bernard , Zackery Riley , Simon Smith , Paul Wohnoutka , Michael J Hawrylycz , Luis Puelles , Allan R Jones |
2014-07-16 | - |
| 24763282 |
FRA2A is a CGG repeat expansion associated with silencing of AFF3. PLoS Genet. Sofie Metsu , Liesbeth Rooms , Jacqueline Rainger , Martin S Taylor , Hemant Bengani , David I Wilson , Chandra Sekhar Reddy Chilamakuri , Harris Morrison , Geert Vandeweyer , Edwin Reyniers , Evelyn Douglas , Geoffrey Thompson , Eric Haan , Jozef Gecz , David R Fitzpatrick , R Frank Kooy |
2014-04-01 | - |
| 25162227 |
PLoS ONE Justin M Moore , Peter L Oliver , Mattéa J Finelli , Sheena Lee , Tom Lickiss , Zoltán Molnár , Kay E Davies |
2014-01-01 | - |
| 22417325 |
Detection of genes regulated by Lmx1b during limb dorsalization. Dev. Growth Differ. Jennifer M Feenstra , Kohei Kanaya , Charmaine U Pira , Sarah E Hoffman , Richard J Eppey , Kerby C Oberg |
2012-05-01 |
Acan,
Apod,
Cbln2,
Col11a2,
Col9a3,
Dcn,
Emx2,
Gdf5,
Kera,
Aff3,
Lect1,
Lmx1b,
Lox,
Lum,
Matn1,
Matn4,
Meis1,
Nog,
Scin,
Efemp1,
Fam196b,
Rfx4,
Hoxd3os1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21386911 |
PLoS ONE Rathi D Thiagarajan , Kylie M Georgas , Bree A Rumballe , Emmanuelle Lesieur , Han Sheng Chiu , Darrin Taylor , Dave T P Tang , Sean M Grimmond , Melissa H Little |
2011-01-01 |
1110002E22Rik,
Emilin1,
Itga9,
Smek2,
Slc17a3,
Gpsm3,
Me2,
Kazald1,
Aldh1l1,
Ccdc86,
Mybpc1,
Npy,
Slc18a1,
Ugt2b37,
Foxp2,
Ace,
Ehbp1l1,
Slc13a3,
Adcy8,
Ambp,
Acsm1,
Apoa4,
Nr2f2,
Synpo2,
Bmp2,
C2,
Cacnb4,
Capg,
Casp4,
Entpd5,
Cdh11,
Cideb,
Col3a1,
Col9a1,
Csrp1,
Cyp1b1,
Cyp4a10,
Dkk1,
Dpep1,
S1pr3,
Eya1,
F10,
Fbp2,
Fbp1,
Slc6a13,
Gpd1,
Gnb4,
Gng2,
Gpm6b,
Gria4,
Gk,
Hdc,
Hhex,
Hoxa10,
Hpgd,
Hpn,
Elavl1,
Elavl4,
Igf1,
Jag1,
Napsa,
Khsrp,
Aff3,
Lgals1,
Lhx1,
Stard4,
Rbm39,
Ly86,
Edaradd,
Kitl,
Mlf1,
Nxph1,
Slc22a6,
Pdgfra,
Pgf,
Prlr,
Pipox,
Ptn,
Ttc36,
Rem1,
Rgs5,
Nr1h4,
Scnn1b,
Sord,
Sema3b,
Slc23a1,
Slc3a1,
Serpini1,
Stc2,
Clic6,
Tcn2,
Tdrd5,
Rassf2,
Mfsd4b1,
BC089597,
Myo15b,
Serpina10,
Tgfb1i1,
Tgfbi
|
| 21801425 |
Analysis of the dynamics of limb transcriptomes during mouse development. BMC Dev. Biol. Istvan Gyurján , Bernhard Sonderegger , Felix Naef , Denis Duboule |
2011-01-01 |
C130021I20Rik,
Cbln1,
Hand2,
Hoxc6,
Aff3,
Lhx9,
Lmx1b,
Nog,
Sox4,
Tmem8c,
Prdm16,
9430024E24Rik
|
| 19334288 |
Dev. Dyn. Alexander N Combes , Emmanuelle Lesieur , Vincent R Harley , Andrew H Sinclair , Melissa H Little , Dagmar Wilhelm , Peter Koopman |
2009-05-01 |
Mfap1b,
Emilin1,
Synpo,
Itga9,
Arl1,
0610010K14Rik,
Ssr1,
4933409K07Rik,
Hdlbp,
Foxp2,
Adam19,
Alas1,
Nr2f2,
Rhoa,
Arpc1b,
Atp5g1,
C1qbp,
C4b,
Canx,
Casq2,
Ccne2,
Cd24a,
Cd2ap,
Entpd5,
Cdh11,
Cdh5,
Cdkn1a,
Cldn5,
Cnbp,
Col14a1,
Col18a1,
Col3a1,
Col4a2,
Col5a2,
Col6a1,
Col9a1,
Hapln1,
Vcan,
Cyp17a1,
Cyp51,
Dcn,
Ddt,
Dhh,
Dkk1,
Adam24,
Phc1,
Egr1,
Enpep,
Epha4,
Fbn1,
Fbn2,
Fbp1,
Gpd1,
Gja1,
Gnb4,
Gria4,
Hbb-bh1,
Hbb-y,
Hoxa10,
Elavl1,
Id1,
Ide,
Igfbp2,
Itga4,
Kcnj8,
Kpna2,
Aff3,
Lama1,
Lamb1,
Lgals1,
Lhx1,
Mfap2,
Man1a2,
Me1,
Nfia,
Nid2,
Ddr2,
Pcnt,
Pdgfra,
Pepd,
Pgam1,
Pou5f1,
Psmc2,
Rspo1,
Ptn,
Igdcc3,
Grhl1,
Sema5a,
Slc2a3,
Slc3a1,
Sox17,
Sox9,
Spint2,
Stc1,
Itih5,
Tbx2,
Tcn2,
Tfdp1,
Tgfb1i1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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