| Type | Description |
|---|---|
| Definition | DNA fragmentation factor subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:16:00 | Glandular, menopause-independent DFF40, DFF45, and Bcl-2 overexpression may play an important role in the pathogenesis of endometrial polyps and benign endometrial hyperplasia | 28914671 |
| 2017-12-09 12:47:00 | evaluate the relative expression levels of miR-196a2 and three of its selected apoptosis-related targets; ANXA1, DFFA and PDCD4 in a sample of GI cancer patients | 29091952 |
| 2015-10-31 11:04:00 | Data show that the caspase-activated DNase (CAD) is activated when caspases cleave its endogenous inhibitor ICAD, resulting in the characteristic DNA laddering of apoptosis. | 26106156 |
| 2014-08-09 10:12:00 | Data suggest that DFF45 gene silencing, when applied in combination with doxorubicin, may offer a therapeutic strategy for the treatment of breast cancer. | 24277473 |
| 2014-01-25 12:20:00 | ICAD deficiency was associated with severe genomic instability. | 23451280 |
| Type | IDs |
|---|---|
| Synonymous | DFF-45, DFF1, ICAD |
| Gene |
UniProtKB-ID:
DFFA_HUMAN,
A0A024R4H5_HUMAN
UniprotKB:
O00273,
A0A024R4H5
UniParc:
UPI000002A7D6,
UPI00001291FA
EMBL:
CH471130,
AF103799,
AK313317,
AF087573,
BC000037,
BT006980,
BC007112,
BC007721,
AL354956,
U91985
Ensembl:
ENSG00000160049
KO:
hsa:1676
|
| Nucleutide sequences |
EMBL-CDS:
AAD32953.1,
AAH07112.1,
EAW71657.1,
AAC51249.1,
BAG36122.1,
AAF02419.1,
AAH07721.1,
EAW71656.1,
AAH00037.1,
AAP35626.1,
EAW71658.1
Gene_ORFName:
H13,
hCG_25280
Ensembl_TRS:
ENST00000377036,
ENST00000377038
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366235,
ENSP00000366237
RefSeq:
NP_004392.1,
NP_998731.1
|
| Others |
UniRef100:
UniRef100_O00273,
UniRef100_A0A024R4H5
UniRef90:
UniRef90_O00273
UniRef50:
UniRef50_O00273
UniGene:
Hs.484782
CCDS:
CCDS118.1,
CCDS119.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员