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167227 DCP2

167227

DCP2

decapping mRNA 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition decapping mRNA 2

研究结论

Date Results Publications
2019-06-29 10:48:00 Human MARF1 is an endoribonuclease that interacts with the DCP1:DCP2 decapping complex and degrades target mRNAs. 30364987
2015-08-08 10:04:00 Human Dcp2 levels and activity are controlled by a competition between decapping complex assembly and Dcp2 degradation. 25870104
2014-07-26 12:45:00 The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells. 24510189
2013-06-08 10:40:00 Data show that Y14 interacts directly with the decapping factor Dcp2 and the 5' cap structure of mRNAs via different but overlapping domains. 23115303
2013-05-18 11:05:00 PNRC2 acts in synergy with Dcp1a to stimulate the decapping activity of Dcp2 by bridging the interaction between Dcp1a and Dcp2. 23085078

名称对应

Type IDs
Synonymous NUDT20
Gene
UniProtKB-ID: DCP2_HUMAN
UniprotKB: Q8IU60
UniParc: UPI00000747DA, UPI0000231C54
EMBL: AK090564, AY146650, BC064593, AC008536, BC045596, AY135173
Ensembl: ENSG00000172795
KO: hsa:167227
Nucleutide sequences
EMBL-CDS: BAC03479.1, AAH45596.1, AAH64593.1, AAN08884.1, AAN62762.1
Ensembl_TRS: ENST00000389063, ENST00000515408
Protein sequencees
Ensembl_PRO: ENSP00000373715, ENSP00000425770
RefSeq: XP_016864652.1, NP_689837.2, NP_001229306.1
Others
UniRef100: UniRef100_Q8IU60
UniRef90: UniRef90_Q8IU60
UniRef50: UniRef50_Q8IU60
UniGene: Hs.443875
CCDS: CCDS56377.1, CCDS34210.1

全选

研究热度
发表文献
热点单位
排名 科研单位 文献
1

Rutgers University

6
2

University of Colorado

5
3

University of Toronto

4
4

Howard Hughes Medical Institute

3
5

Max Planck Institute for Developmental Biology

3
热点人员
排名 研究人员 文献
1

Megerditch Kiledjian

6
2

Jens Lykke-Andersen

4
3

Matthias Mann

3
4

Anne-Claude Gingras

3
5

Xinfu Jiao

3
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