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1671 DEFA6

1671

DEFA6

defensin alpha 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition defensin alpha 6

研究结论

Date Results Publications
2020-10-31 13:16:00 Upregulated Expression of Intestinal Antimicrobial Peptide HD5 Associated with Renal Function in IgA Nephropathy. 32089753
2019-08-24 10:05:00 DEFA6 is associated with overall survival rate of CRC patients and thus an independent prognostic marker for CRC. These results suggest that DEFA6 plays an essential oncogenic role in CRC and serves a good therapeutic target for the disease. 30932884
2019-05-11 12:14:00 In contrast to oxidized peptides, some reduced defensins exhibit increased vulnerability to proteolytic degradation. In this report, we investigated the susceptibility of Paneth-cell-specific human alpha-defensin 5 (HD-5) and -6 (HD-6) to intestinal proteases using natural human duodenal fluid 30808760
2017-12-16 12:11:00 HD6 assembled into nanonets can prevent key steps in C. albicans pathogenesis 28198610
2017-05-20 14:20:00 alpha-Defensin 6 Self-Assembly Prevents Adhesion and Suppresses Virulence Traits of Candida albicans 28026958

名称对应

Type IDs
Synonymous DEF6, HD-6
Gene
UniProtKB-ID: DEF6_HUMAN
UniprotKB: Q01524
UniParc: UPI0000129125
EMBL: U33317, BC069769, M98331, BC069710, AF200455, BC069667, BC069728, BC093951, CH471153, BC093953
Ensembl: ENSG00000285136, ENSG00000164822
KO: hsa:1671
Nucleutide sequences
EMBL-CDS: AAC50382.1, EAW80484.1, AAH69710.1, AAH93953.1, AAB59357.1, AAH69769.1, AAH69728.1, AAT68876.1, AAH69667.1, AAH93951.1
Ensembl_TRS: ENST00000646187, ENST00000297436
Protein sequencees
Ensembl_PRO: ENSP00000494361, ENSP00000297436
RefSeq: NP_001917.1
Others
UniRef100: UniRef100_Q01524
UniRef90: UniRef90_Q01524
UniRef50: UniRef50_Q01524
UniGene: Hs.711
CCDS: CCDS5960.1

全选

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