Type | Description |
---|---|
Definition | defensin alpha 4 |
Date | Results | Publications |
---|---|---|
2019-11-30 10:58:00 | findings unveil the molecular determinants of HNP4 function, completing the atlas of structure and function relationships for all human neutrophil alpha-defensins. | 30658057 |
2019-09-14 10:08:00 | Three AMP genes, histatin 3 (HTN3), alpha-defensin 4 (DEFA4) and lysozyme C (LYZ), presented different expression levels in periodontitis patients compared with healthy subjects. The relative expression level of DEFA4 appeared to be a protective factor against periodontitis. | 29446150 |
2014-10-03 16:19:00 | DEFA4 displays antimicrobial activity against E. coli, S. faecalis, and C. albicans. | 2500436 |
2013-05-25 10:31:00 | Results indicate that the gene expression of DEFA 1/3 and 4 was significantly increased in all tumours - except for a significant decrease of DEFA 4 gene expression in pleomorphic adenomas. | 23050799 |
2011-10-29 10:21:00 | DEFA1-3 and DEFA4 mRNA level in peripheral blood cells can be used to identify chronic myeloid leukaemia patients who are at risk of being imatinib-resistant, before initiation of the therapy. | 21734341 |
Type | IDs |
---|---|
Synonymous | DEF4, HNP-4, HP-4, HP4 |
Gene |
UniProtKB-ID:
DEF4_HUMAN
UniprotKB:
P12838
UniParc:
UPI0000034C36
EMBL:
U18745,
BC106747,
X65977,
AF200455,
BC093959,
CH471153,
BC112091
Ensembl:
ENSG00000285318,
ENSG00000164821
KO:
hsa:1669
|
Nucleutide sequences |
EMBL-CDS:
AAH93959.1,
AAI12092.1,
AAT68877.1,
CAA46792.1,
AAI06748.1,
EAW80486.1,
AAA64488.1
Ensembl_TRS:
ENST00000297435,
ENST00000642522
|
Protein sequencees |
Ensembl_PRO:
ENSP00000493844,
ENSP00000297435
RefSeq:
NP_001916.1
|
Others |
UniRef100:
UniRef100_P12838
UniRef90:
UniRef90_P12838
UniRef50:
UniRef50_P12838
UniGene:
Hs.591391
CCDS:
CCDS5961.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员