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1669 DEFA4

1669

DEFA4

defensin alpha 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition defensin alpha 4

研究结论

Date Results Publications
2019-11-30 10:58:00 findings unveil the molecular determinants of HNP4 function, completing the atlas of structure and function relationships for all human neutrophil alpha-defensins. 30658057
2019-09-14 10:08:00 Three AMP genes, histatin 3 (HTN3), alpha-defensin 4 (DEFA4) and lysozyme C (LYZ), presented different expression levels in periodontitis patients compared with healthy subjects. The relative expression level of DEFA4 appeared to be a protective factor against periodontitis. 29446150
2014-10-03 16:19:00 DEFA4 displays antimicrobial activity against E. coli, S. faecalis, and C. albicans. 2500436
2013-05-25 10:31:00 Results indicate that the gene expression of DEFA 1/3 and 4 was significantly increased in all tumours - except for a significant decrease of DEFA 4 gene expression in pleomorphic adenomas. 23050799
2011-10-29 10:21:00 DEFA1-3 and DEFA4 mRNA level in peripheral blood cells can be used to identify chronic myeloid leukaemia patients who are at risk of being imatinib-resistant, before initiation of the therapy. 21734341

名称对应

Type IDs
Synonymous DEF4, HNP-4, HP-4, HP4
Gene
UniProtKB-ID: DEF4_HUMAN
UniprotKB: P12838
UniParc: UPI0000034C36
EMBL: U18745, BC106747, X65977, AF200455, BC093959, CH471153, BC112091
Ensembl: ENSG00000285318, ENSG00000164821
KO: hsa:1669
Nucleutide sequences
EMBL-CDS: AAH93959.1, AAI12092.1, AAT68877.1, CAA46792.1, AAI06748.1, EAW80486.1, AAA64488.1
Ensembl_TRS: ENST00000297435, ENST00000642522
Protein sequencees
Ensembl_PRO: ENSP00000493844, ENSP00000297435
RefSeq: NP_001916.1
Others
UniRef100: UniRef100_P12838
UniRef90: UniRef90_P12838
UniRef50: UniRef50_P12838
UniGene: Hs.591391
CCDS: CCDS5961.1

全选

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