| Type | Description |
|---|---|
| Definition | defensin alpha 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-08 10:14:00 | lower DEFA1/DEFA3 copy number (CNV < 7) is associated with higher susceptibility to hospital-acquired infections (HAIs) in critically ill patients, indicating that host genetic factors are involved in the development of HAIs | 29950924 |
| 2018-02-24 10:18:00 | DEFA1, DEFA3, and PPBP expression was significantly increased in hyperlipidemia and coronary heart disease patients compared with controls. | 28420383 |
| 2017-07-29 10:58:00 | these results demonstrate that HNPs1-3 may be potent inhibitors of ADAMTS13 activity, likely by binding to the central A2 domain of VWF and physically blocking ADAMTS13 binding. | 27207796 |
| 2017-02-25 12:13:00 | High HNP3 expression is associated with IgA Nephropathy. | 27563166 |
| 2015-08-08 10:35:00 | The expression of alpha-defensins 1, 2 and 3 is up-regulated in hypercholesteremia. | 25300997 |
| Type | IDs |
|---|---|
| Synonymous | DEF3, HNP-3, HNP3, HP-3, HP3 |
| Gene |
UniProtKB-ID:
DEF3_HUMAN,
Q6EZE9_HUMAN
UniprotKB:
P59666,
Q6EZE9
UniParc:
UPI00001405CC
EMBL:
BC119706,
BC027917,
M21131,
X13621,
M23281,
AF200455,
L12691,
AF238378
Ensembl:
ENSG00000239839
KO:
hsa:1668
|
| Nucleutide sequences |
EMBL-CDS:
AAB57722.1,
AAA52304.1,
AAA35753.2,
CAA31952.1,
AAH27917.1,
AAI19707.1,
AAT68881.1,
AAT68885.1
Ensembl_TRS:
ENST00000327857
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000328359
RefSeq:
NP_005208.1,
XP_011533043.1
|
| Others |
UniRef100:
UniRef100_P59666
UniRef90:
UniRef90_P59665
UniRef50:
UniRef50_P59665
UniGene:
Hs.654448
CCDS:
CCDS5962.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员