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16668 Krt18

16668

Krt18

keratin 18

protein-coding

Mus musculus

基因描述

Type Description
Definition keratin 18

研究结论

Date Results Publications
2020-05-09 12:06:00 Krt18 plays a complementary role to Krt19 in skeletal muscle in both assembling keratin-based filaments and transducing contractile force. 31721615
2018-11-10 10:43:00 Cumulatively, these data indicate that altered CK14 (high) and CK18 (low) expression is perhaps an early event in bladder cancer tumorigenesis in females at least and is characteristic of both urothelial superficial pre-neoplastic and neoplastic lesions. 29350066
2018-03-10 11:51:00 K18 deficiency of hepatocytes leads to steatosis, increasing with age, and finally to SH. K18 deficiency and age promote liver tumor development in mice, frequently on the basis of chromosomal instability, resembling human HCC with stemness features. 27689336
2017-08-12 11:05:00 K8/K18-dependent and ASMase-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 loss. 27422101
2016-05-28 11:32:00 autoantibodies were detected in aging K18-null male mice that had a related liver phenotype but normal colon compared with K8-null mice, suggesting that the autoantibodies are linked to liver rather than colonic disease 26399787

名称对应

Type IDs
Synonymous CK18, K18, Krt1-18
Gene
UniProtKB-ID: K1C18_MOUSE
UniprotKB: P05784
UniParc: UPI000016CD33
EMBL: AK145413, AK167072, AK167265, AK167432, M36376, AK167469, M11686, BC089022, Y00217, AK167676, M22832
Ensembl: ENSMUSG00000023043
KO: mmu:16668
Nucleutide sequences
EMBL-CDS: BAE39519.1, AAA37552.1, CAA68365.1, BAE26424.1, AAA39390.1, BAE39378.1, BAE39232.1, BAE39725.1, BAE39553.1, AAA39373.1, AAH89022.1
Ensembl_TRS: ENSMUST00000023803
Protein sequencees
Ensembl_PRO: ENSMUSP00000023803
RefSeq: NP_034794.2
Others
UniRef100: UniRef100_P05784
UniRef90: UniRef90_P05784
UniRef50: UniRef50_P05784
UniGene: Mm.22479
CCDS: CCDS27869.1

全选

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