| Type | Description |
|---|---|
| Definition | sarcospan |
| Date | Results | Publications |
|---|---|---|
| 2018-03-31 10:20:00 | An alternatively spliced isoform of sarcospan localizes to the sarcoplasmic reticulum in skeletal muscle. It is absent in Sgcd-/- skeletal muscle, a murine model for limb girdle muscular dystrophy 2F. | 28587652 |
| 2017-06-10 11:38:00 | these results demonstrate that SSPN overexpression is well tolerated in mdx mice and improves sarcolemma defects that underlie skeletal muscle and pulmonary dysfunction in Duchenne muscular dystrophy | 27798107 |
| 2016-09-17 10:22:00 | regulates cardiac isoproterenol response and prevents Duchenne muscular dystrophy-associated cardiomyopathy | 26702077 |
| 2016-01-16 11:10:00 | Sarcospan-mediated amelioration of muscular dystrophy in mouse model is dependent on the presence of both utrophin and alpha7beta1 integrin. | 25504048 |
| 2013-06-22 10:05:00 | SSPN is a necessary component of dystrophin and Utr function and that SSPN modulation of integrin signaling is required for extracellular matrix attachment and muscle force development. | 22798625 |
| Type | IDs |
|---|---|
| Synonymous | Krag |
| Gene |
UniProtKB-ID:
SSPN_MOUSE,
Q3TRE0_MOUSE,
E9Q8Y7_MOUSE,
Q3TPB3_MOUSE
UniprotKB:
Q62147,
Q3TRE0,
E9Q8Y7,
Q3TPB3
UniParc:
UPI00015AA4A6,
UPI0000028911,
UPI000002343D,
UPI00005B2095
EMBL:
U02485,
U02487,
AK164529,
AK148179,
AK164430,
AC144936,
U02486,
AK162864,
AK163041,
U02484
Ensembl:
ENSMUSG00000030255
KO:
mmu:16651
|
| Nucleutide sequences |
EMBL-CDS:
AAB60682.1,
AAA03712.1,
BAE37167.1,
BAE37784.1,
BAE37090.1,
BAE28399.1,
BAE37824.1
Ensembl_TRS:
ENSMUST00000032383,
ENSMUST00000111702,
ENSMUST00000111701
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032383,
ENSMUSP00000107331,
ENSMUSP00000107330
RefSeq:
NP_034786.1,
NP_001297766.1,
XP_036021786.1,
XP_006506979.1
|
| Others |
UniRef100:
UniRef100_Q62147,
UniRef100_Q3TRE0
UniRef90:
UniRef90_Q62147
UniRef50:
UniRef50_Q62147
UniGene:
Mm.49689
CCDS:
CCDS20698.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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