| Type | Description |
|---|---|
| Definition | DEAH-box helicase 15 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:40:00 | RNA affinity, helicase, and ATPase activity of DHX15 are increased when the G-patch motif of NKRF binds in an extended conformation across the helicase surface | 32179686 |
| 2020-06-06 13:56:00 | The DHX15 selectively binds PAMP RNA to promote RIG-I ATP hydrolysis and signaling activation in response to viral RNA. The results define DHX15 as a coreceptor required for RLR innate immune responses to control RNA virus infection. | 31090472 |
| 2019-11-16 11:57:00 | these findings demonstrate, for the first time, that DHX15 is significantly upregulated in hepatocellular carcinoma and its high expression was correlated with poor prognosis, suggesting its pivotal role in the progression of hepatocellular carcinoma | 30339968 |
| 2019-10-26 11:39:00 | ETS1 and SP1 regulated DHX15 expression in acute lymphoblastic leukaemia. | 29512921 |
| 2019-08-31 11:18:00 | CMTr1 binds ATP-dependent RNA DHX15 helicase and that this interaction, mediated by the G-patch domain of CMTr1, has an advantageous effect on CMTr1 activity towards highly structured RNA substrates. | 30397098 |
| Type | IDs |
|---|---|
| Synonymous | DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p |
| Gene |
UniProtKB-ID:
DHX15_HUMAN
UniprotKB:
O43143
UniParc:
UPI000012907A
EMBL:
AF279891,
BC035974,
AB001636
Ensembl:
ENSG00000109606
KO:
hsa:1665
|
| Nucleutide sequences |
EMBL-CDS:
AAF90182.1,
AAH35974.1,
BAA23987.1
Ensembl_TRS:
ENST00000336812
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000336741
RefSeq:
NP_001349.2
|
| Others |
UniRef100:
UniRef100_O43143
UniRef90:
UniRef90_O43143
UniRef50:
UniRef50_O43143
UniGene:
Hs.696074
CCDS:
CCDS33966.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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