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16644 Kng1

16644

Kng1

kininogen 1

protein-coding

Mus musculus

基因描述

Type Description
Definition kininogen 1

研究结论

Date Results Publications
2019-02-02 12:04:00 Schistosome tegument contains two cysteine proteases belonging to the calpain family (SmCalp1 and SmCalp2) and these are likely responsible for the high molecular weight kininogen (HK) cleavage reported here. Schistosome cleavage of HK should help impede blood clotting and inflammation around the worms in vivo and so promote their ease of movement within the vasculature of their hosts. 29540224
2014-06-07 11:04:00 uPAR mediates efferocytosis through high molecular weight kininogen interaction with phosphatidylserine on apoptotic cells 24688027
2013-01-26 11:15:00 mice deficient in KNG showed less severe blood-brain barrier damage and edema formation, and the local inflammatory response was reduced compared with controls. 22936662
2010-01-21 00:00:00 mKng1 is responsible for production of plasma kininogen 18000168
2010-01-21 00:00:00 Domain 5 of kininogen was identified as an anti-adhesive component with a potent anti-inflammatory action in a peritonitis mouse model. 12023845

名称对应

Type IDs
Synonymous Kng
Gene
UniProtKB-ID: KNG1_MOUSE, D3YTY9_MOUSE, A0A0R4J038_MOUSE
UniprotKB: O08677, D3YTY9, A0A0R4J038
UniParc: UPI00001E3943, UPI0000022030, UPI0000024A44, UPI00002332DF, UPI00000279D8
EMBL: D84435, AY660571, AK005547, BC108936, D84415, AC154540, BC018158, AY462058
Ensembl: ENSMUSG00000022875
KO: mmu:16644
Nucleutide sequences
EMBL-CDS: AAR88632.1, AAT70087.1, BAA19743.1, AAH18158.1, BAA19742.1, AAI08937.1
Ensembl_TRS: ENSMUST00000039492, ENSMUST00000089902, ENSMUST00000023589
Protein sequencees
Ensembl_PRO: ENSMUSP00000040485, ENSMUSP00000087346, ENSMUSP00000023589
RefSeq: XP_006521876.1, XP_030104848.1, NP_075614.1, NP_001095882.1, NP_001095881.1, XP_006521875.1
Others
UniRef100: UniRef100_D3YTY9, UniRef100_A0A0R4J038, UniRef100_O08677
UniRef90: UniRef90_O08677-3, UniRef90_O08677
UniRef50: UniRef50_O08677-3, UniRef50_P08934
UniGene: Mm.2160
CCDS: CCDS28073.1, CCDS49803.1, CCDS49804.1

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