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16640 Klra9

16640

Klra9

killer cell lectin-like receptor subfamily A, member 9

protein-coding

Mus musculus

基因描述

Type Description
Definition killer cell lectin-like receptor subfamily A, member 9

研究结论

Date Results Publications
2019-01-26 11:47:00 Clearance of lung cancer is facilitated by up-regulation of NKG2D, NKp46, and other activating receptors upon exposure to environmental MHCI. Surface expression of the inhibitory receptor Ly49C/I, on the other hand, is down-regulated upon exposure to tumor-bearing tissue. 30381460
2010-01-21 00:00:00 Contrary to findings in other inhibitory LY49 transgenic systems, no defects in T cell function are observed in Ly49I transgenic FVB mice. 12244158
2010-01-21 00:00:00 NK cells' own MHC-I significantly masks the Ly49A and Ly49C, but not the Ly49I receptor. Nevertheless, Ly49I was partly masked on transfected tumor cells, suggesting that the structure of Ly49I is compatible in principal with cis binding of MHC-I. 17237373
2010-01-21 00:00:00 The repertoire of inhibitory Ly49 receptors may be formed under the influenced of Fyn-dependent NK cell activation as well as the respective MHC class I environment. 11870621
2010-01-21 00:00:00 mouse cytomegalovirus(MCMV) m157 protein binds to Ly49I 11950999

名称对应

Type IDs
Synonymous LY49I1, Ly49I
Gene
UniProtKB-ID: KLRA3_MOUSE, Q2TJJ8_MOUSE
UniprotKB: Q64329, Q2TJJ8
UniParc: UPI00000E7E14, UPI000016CB4E
EMBL: BC103544, U56405, BC103543, BC099879, BC103545, AK159595, BC145192, BC099867, BC145193, AC087336, AC090127, BC132526, U49865, BC099880, BC132524, BC099878, U49867, U49866, U09739, U56404, AY860970, U10305, U34891, U49868, BC101952
Ensembl: ENSMUSG00000067591, ENSMUSG00000033024
KO: mmu:16640, mmu:16634
Nucleutide sequences
EMBL-CDS: AAI45194.1, AAI45193.1, AAH99867.1, AAI01953.1, AAI03546.1, AAA92952.1, AAB19100.1, AAI32525.1, AAI32527.1, AAA92951.1, BAE35215.1, AAA92953.1, AAA92954.1, AAI03544.1, AAA19053.1, AAH99880.1, AAI03545.1, AAA86873.1, AAH99878.1, AAH99879.1, AAB19101.1, AAX52172.1, AAA77066.1
Ensembl_TRS: ENSMUST00000088017, ENSMUST00000111998, ENSMUST00000112032, ENSMUST00000071554
Protein sequencees
Ensembl_PRO: ENSMUSP00000085333, ENSMUSP00000107629, ENSMUSP00000107663, ENSMUSP00000071485
RefSeq: XP_036021784.1, XP_011239535.1, NP_034781.2, XP_030111062.1, XP_011239537.1
Others
UniRef100: UniRef100_Q2TJJ8, UniRef100_Q64329
UniRef90: UniRef90_Q64329
UniRef50: UniRef50_Q64329
UniGene: Mm.457996
CCDS: CCDS20601.1

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