Type | Description |
---|---|
Definition | killer cell lectin-like receptor, subfamily A, member 3 |
Date | Results | Publications |
---|---|---|
2019-05-04 11:34:00 | The Ly49 family of class I MHC receptors have critical role for adaptive natural killer cell responses. | 30249666 |
2019-01-26 11:47:00 | Clearance of lung cancer is facilitated by up-regulation of NKG2D, NKp46, and other activating receptors upon exposure to environmental MHCI. Surface expression of the inhibitory receptor Ly49C/I, on the other hand, is down-regulated upon exposure to tumor-bearing tissue. | 30381460 |
2017-05-20 13:46:00 | This docking mode was conserved with that previously observed for Ly49C.H-2K(b) Indeed, structure-guided mutation of Ly49C indicated that Ly49C.H2-Q10 and Ly49C.H-2K(b) possess similar energetic footprints focused around residues located within the Ly49C beta4-stand and L5 loop, which contact the underside of the peptide-binding platform floor. | 27385590 |
2014-11-29 11:47:00 | murine cytomegalovirus infection results in altered NK cell activation | 24873973 |
2013-11-16 11:54:00 | we have shown for the first time how the differential expression of the Ly49 inhibitory receptors during ontogeny can affect NK cell function | 23960238 |
Type | IDs |
---|---|
Synonymous | 5E6, Ly49c, NK-2.1, Nk-2, Nk2, Nk2.1 |
Gene |
UniProtKB-ID:
KLRA3_MOUSE
UniprotKB:
Q64329
UniParc:
UPI00000E7E14
EMBL:
U49868,
U10305,
U56404,
BC101952,
BC099880,
U49865,
BC132526,
U49866,
U09739,
U49867,
BC099878,
BC132524,
BC145192,
AK159595,
BC145193,
BC099867,
AC087336,
BC099879,
BC103545,
BC103544,
U56405,
BC103543
Ensembl:
ENSMUSG00000067591
KO:
mmu:16640,
mmu:16634
|
Nucleutide sequences |
EMBL-CDS:
AAI45194.1,
AAI45193.1,
AAH99867.1,
AAI01953.1,
AAI03546.1,
AAA92952.1,
AAB19100.1,
AAI32525.1,
AAI32527.1,
AAA92951.1,
BAE35215.1,
AAA92953.1,
AAA92954.1,
AAI03544.1,
AAA19053.1,
AAH99880.1,
AAI03545.1,
AAA86873.1,
AAH99878.1,
AAH99879.1,
AAB19101.1
Ensembl_TRS:
ENSMUST00000088017,
ENSMUST00000111998
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000085333,
ENSMUSP00000107629
RefSeq:
NP_001276533.1,
NP_034778.2,
NP_001276534.1
|
Others |
UniRef100:
UniRef100_Q64329
UniRef90:
UniRef90_Q64329
UniRef50:
UniRef50_Q64329
UniGene:
Mm.425338,
Mm.457996
CCDS:
CCDS20601.1
|
排名 | 科研单位 | 文献 |
---|---|---|
1 |
Washington University School of Medicine |
4 |
2 |
National Cancer Institute |
3 |
3 |
University of Ottawa |
2 |
4 |
Howard Hughes Medical Institute |
2 |
5 |
University of Virginia |
2 |
排名 | 研究人员 | 文献 |
---|---|---|
1 |
P Carninci |
7 |
2 |
Y Hayashizaki |
6 |
3 |
W M Yokoyama |
6 |
4 |
K Shibata |
5 |
5 |
M Itoh |
5 |