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16634 Klra3

16634

Klra3

killer cell lectin-like receptor, subfamily A, member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition killer cell lectin-like receptor, subfamily A, member 3

研究结论

Date Results Publications
2019-05-04 11:34:00 The Ly49 family of class I MHC receptors have critical role for adaptive natural killer cell responses. 30249666
2019-01-26 11:47:00 Clearance of lung cancer is facilitated by up-regulation of NKG2D, NKp46, and other activating receptors upon exposure to environmental MHCI. Surface expression of the inhibitory receptor Ly49C/I, on the other hand, is down-regulated upon exposure to tumor-bearing tissue. 30381460
2017-05-20 13:46:00 This docking mode was conserved with that previously observed for Ly49C.H-2K(b) Indeed, structure-guided mutation of Ly49C indicated that Ly49C.H2-Q10 and Ly49C.H-2K(b) possess similar energetic footprints focused around residues located within the Ly49C beta4-stand and L5 loop, which contact the underside of the peptide-binding platform floor. 27385590
2014-11-29 11:47:00 murine cytomegalovirus infection results in altered NK cell activation 24873973
2013-11-16 11:54:00 we have shown for the first time how the differential expression of the Ly49 inhibitory receptors during ontogeny can affect NK cell function 23960238

名称对应

Type IDs
Synonymous 5E6, Ly49c, NK-2.1, Nk-2, Nk2, Nk2.1
Gene
UniProtKB-ID: KLRA3_MOUSE
UniprotKB: Q64329
UniParc: UPI00000E7E14
EMBL: U49868, U10305, U56404, BC101952, BC099880, U49865, BC132526, U49866, U09739, U49867, BC099878, BC132524, BC145192, AK159595, BC145193, BC099867, AC087336, BC099879, BC103545, BC103544, U56405, BC103543
Ensembl: ENSMUSG00000067591
KO: mmu:16640, mmu:16634
Nucleutide sequences
EMBL-CDS: AAI45194.1, AAI45193.1, AAH99867.1, AAI01953.1, AAI03546.1, AAA92952.1, AAB19100.1, AAI32525.1, AAI32527.1, AAA92951.1, BAE35215.1, AAA92953.1, AAA92954.1, AAI03544.1, AAA19053.1, AAH99880.1, AAI03545.1, AAA86873.1, AAH99878.1, AAH99879.1, AAB19101.1
Ensembl_TRS: ENSMUST00000088017, ENSMUST00000111998
Protein sequencees
Ensembl_PRO: ENSMUSP00000085333, ENSMUSP00000107629
RefSeq: NP_001276533.1, NP_034778.2, NP_001276534.1
Others
UniRef100: UniRef100_Q64329
UniRef90: UniRef90_Q64329
UniRef50: UniRef50_Q64329
UniGene: Mm.425338, Mm.457996
CCDS: CCDS20601.1

全选

研究热度
发表文献
热点单位
排名 科研单位 文献
1

Washington University School of Medicine

4
2

National Cancer Institute

3
3

University of Ottawa

2
4

Howard Hughes Medical Institute

2
5

University of Virginia

2
热点人员
排名 研究人员 文献
1

P Carninci

7
2

Y Hayashizaki

6
3

W M Yokoyama

6
4

K Shibata

5
5

M Itoh

5
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