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1662 DDX10

1662

DDX10

DEAD-box helicase 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition DEAD-box helicase 10

研究结论

Date Results Publications
2020-10-31 13:17:00 [DDX10 promotes AIM2-inflammasome activation by maintaining AIM2 protein stability]. 32519665
2019-12-14 10:38:00 Up-regulation of DDX10 involves in poor prognosis in osteosarcoma (OS) patients and knockdown of DDX10 inhibits cell proliferation in OS. Down-regulation of DDX10 suppressed cell proliferation, invasion and migration in osteosarcoma, which might be regulated by MAPK signalling pathway. 30738579
2016-05-28 11:32:00 Taken together, in current study, we found a novel tumor suppressor, DDX10, is epigenetic silenced by miR-155-5p in ovarian cancer, and the down-regulated expression pattern of DDX10 promotes ovarian cancer proliferation through Akt/NF-kappaB pathway. 26713367
2012-04-26 16:08:00 A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. 22360420
2010-05-07 15:04:00 The 50S U3 snoRNP is an small subunit assembly intermediate that is likely recruited to the pre-rRNA through the RNA-binding proteins nucleolin and RRP5.[RRP5, DBP4] 19332556

名称对应

Type IDs
Synonymous Dbp4, HRH-J8
Gene
UniProtKB-ID: DDX10_HUMAN
UniprotKB: Q13206
UniParc: UPI0000140E62
EMBL: U28042, BC093656, BC091521, AB040537, CH471065, BC093654, AK315216
Ensembl: ENSG00000178105
KO: hsa:1662
Nucleutide sequences
EMBL-CDS: AAH93656.1, EAW67122.1, BAB18536.1, AAH91521.1, AAH93654.1, AAC50823.1, BAG37650.1
Ensembl_TRS: ENST00000322536
Protein sequencees
Ensembl_PRO: ENSP00000314348
RefSeq: NP_004389.2
Others
UniRef100: UniRef100_Q13206
UniRef90: UniRef90_Q13206
UniRef50: UniRef50_Q13206
UniGene: Hs.591931
CCDS: CCDS8342.1

全选

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