| Type | Description |
|---|---|
| Definition | TLE family member 5, transcriptional modulator |
| Date | Results | Publications |
|---|---|---|
| 2017-09-30 12:04:00 | Results suggest that amino enhancer of split protein (AES) plays an important role in controlling tumor growth and metastasis of prostate cancer (PCa) by regulating both androgen receptor (AR) and Notch signaling pathway. | 28178391 |
| 2017-02-18 11:16:00 | results indicate that Aes may belong to a novel family of metastasis suppressors with a CpG-island promoter enhancer, and it is regulated transcriptionally | 27561171 |
| 2016-10-01 10:31:00 | heat shock cognate 70 (HSC70) is an essential component of Aes foci in colorectal cancer cells. | 26229111 |
| 2016-03-26 10:35:00 | AES is a transcriptional repressor for HNF-1-alpha in pancreatic beta-cell. | 26549228 |
| 2014-02-15 10:49:00 | AES binds to PROP1 and represses its expression; PROP1 mutation is a likely cause of combined pituitary hormone deficiency. | 23732115 |
| Type | IDs |
|---|---|
| Synonymous | AES, AES-1, AES-2, ESP1, GRG, GRG5, Grg-5 |
| Gene |
UniProtKB-ID:
TLE5_HUMAN,
Q8WY48_HUMAN
UniprotKB:
Q08117,
Q8WY48
UniParc:
UPI00001AE637,
UPI0000043C26,
UPI000006E9C8
EMBL:
U88831,
AK094591,
AC005944,
BC113735,
U04241,
CH471139,
AF269289,
AF072902,
BC113737,
X73358,
U88832,
AK314713
Ensembl:
ENSG00000104964
KO:
hsa:166
|
| Nucleutide sequences |
EMBL-CDS:
EAW69347.1,
AAD00654.1,
EAW69345.1,
BAG52894.1,
AAI13736.1,
CAA51768.1,
AAC35517.1,
BAG37257.1,
AAA16223.1,
AAI13738.1,
AAC72103.1,
AAG23172.1
Ensembl_TRS:
ENST00000327141,
ENST00000221561
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000221561,
ENSP00000317537
RefSeq:
NP_001121.2,
NP_945321.1,
XP_006722727.1,
NP_945320.1
|
| Others |
UniRef100:
UniRef100_Q8WY48,
UniRef100_Q08117
UniRef90:
UniRef90_Q8WY48,
UniRef90_Q08117
UniRef50:
UniRef50_Q8WY48,
UniRef50_Q08117
UniGene:
Hs.515053
CCDS:
CCDS12101.1,
CCDS12102.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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