Type | Description |
---|---|
Definition | Kruppel-like factor 1 (erythroid) |
Date | Results | Publications |
---|---|---|
2019-11-30 12:16:00 | Study shows that embryos from KLF1 Nan variant have defects in erythroid maturation. | 30921348 |
2019-11-02 10:25:00 | Mutant Nan-KLF1 leads to extensive and progressive transcriptome corruption in adult spleen erythroid precursors such that stress erythropoiesis is severely compromised. | 30143664 |
2019-09-14 12:37:00 | Insight into the mechanism of Congenital Dyserythropoietic Anemia Type IV which is caused by a point mutation in the DNA-binding domain of KLF1. This mutation alters the DNA binding specificity of KLF1 and this leads to aberrant binding in vivo at a few thousand sites scattered across the genome. | 31126231 |
2019-08-24 11:05:00 | data indicate that the cytotoxic effect of IFN-beta activation in CMEI contribute to the impairment of definitive erythropoiesis associated with Klf1 deprivation | 29230002 |
2019-01-12 10:08:00 | Results provide new evidence to support a role for KLF1 in the erythroid/megakaryocyte switch, as well as indicating that transcription factor competition is an important regulation mechanism in eukaryotes in vivo. | 28600522 |
Type | IDs |
---|---|
Synonymous | Eklf, Nan |
Gene |
UniProtKB-ID:
E9QNP6_MOUSE,
A0A6I8MWY6_MOUSE
UniprotKB:
E9QNP6,
A0A6I8MWY6
UniParc:
UPI000002166F,
UPI0000357F02
EMBL:
AC161765
Ensembl:
ENSMUSG00000054191
KO:
mmu:16596
|
Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000067060,
ENSMUST00000239392
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000064366,
ENSMUSP00000159324
RefSeq:
NP_034765.3
|
Others |
UniRef100:
UniRef100_A0A6I8MWY6
UniRef90:
UniRef90_P46099
UniRef50:
UniRef50_Q13351
UniGene:
Mm.4847
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
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