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16593 Klc1

16593

Klc1

kinesin light chain 1

protein-coding

Mus musculus

基因描述

Type Description
Definition kinesin light chain 1

研究结论

Date Results Publications
2020-12-19 13:40:00 Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance. 32265198
2020-02-15 12:50:00 DOC2B collaborates with KLC1 to regulate insulin-stimulated GLUT4 accumulation at the plasma membrane and regulates insulin sensitivity 30707251
2019-02-16 10:20:00 kinesin-1 recognizes a novel class of adaptor motifs 'Y-acidic' (tyrosine flanked by acidic residues), in a KLC-isoform-specific manner. 30320553
2018-02-10 11:29:00 KLC1 deletion leads to a reduction of Mn2+ transport from CA3 to the septal nuclei. 27751944
2018-01-27 10:11:00 Phosphorylation of KLC1 at Thr466 increased in aged brains, and JIP1 binding to kinesin-1 decreased, suggesting that APP transport is impaired by aging. Authors conclude that phosphorylation of KLC1 at Thr466 regulates the velocity of transport of APP by kinesin-1 by modulating its interaction with JIP1b. 29093025

名称对应

Type IDs
Synonymous AI874768, Kns2
Gene
UniProtKB-ID: Q8CD76_MOUSE, Q7M702_MOUSE, Q7TNF4_MOUSE, Q7M6Z7_MOUSE, E9Q7C9_MOUSE, Q7M6Z8_MOUSE, Q7M701_MOUSE, Q7M6Z9_MOUSE, Q5UE59_MOUSE
UniprotKB: Q8CD76, Q7M702, Q7TNF4, Q7M6Z7, E9Q7C9, Q7M6Z8, Q7M701, Q7M6Z9, Q5UE59
UniParc: UPI0001611538, UPI00001D9725, UPI00001B9472, UPI0000451B9B, UPI00001D9729, UPI00001D9727, UPI00001D9728, UPI00000E92A2, UPI00001D9724
EMBL: BC055744, BK000673, AK031309, AC152065, BK000670, AY753300, BK000669, BK000672, BK000674
Ensembl: ENSMUSG00000021288
KO: mmu:16593
Nucleutide sequences
EMBL-CDS: BAC27341.1, DAA01270.1, AAH55744.1, DAA01275.1, DAA01274.1, DAA01271.1, DAA01273.1, AAV30550.1
Ensembl_TRS: ENSMUST00000084941, ENSMUST00000122300, ENSMUST00000120544, ENSMUST00000118471
Protein sequencees
Ensembl_PRO: ENSMUSP00000082004, ENSMUSP00000113997, ENSMUSP00000113237, ENSMUSP00000113171
RefSeq: NP_001020534.2, NP_001348538.1, NP_001020530.2, XP_036013092.1, XP_030102426.1, XP_006515557.1, NP_001020531.2, NP_001348541.1, NP_001020529.2, NP_001348534.1, NP_001348540.1, NP_001075428.1, XP_036013091.1, NP_001348542.1, XP_030102425.1, XP_036013090.1, NP_001348539.1, NP_001348543.1, NP_032476.2, NP_001020532.2, NP_001020533.2
Others
UniRef100: UniRef100_Q7M701, UniRef100_Q5UE59, UniRef100_Q7TNF4, UniRef100_E9Q7C9, UniRef100_Q7M6Z7, UniRef100_Q7M6Z9, UniRef100_Q7M702, UniRef100_Q8CD76, UniRef100_Q7M6Z8
UniRef90: UniRef90_O88447, UniRef90_Q07866-9, UniRef90_Q5UE59
UniRef50: UniRef50_Q07866-9, UniRef50_P37285, UniRef50_A0A2D0QMU1
UniGene: Mm.278357

全选

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