| Type | Description |
|---|---|
| Definition | ring finger protein 168 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells. | 32502756 |
| 2021-02-02 13:25:00 | SET8 localization to chromatin flanking DNA damage is dependent on RNF168 ubiquitin ligase. | 31760894 |
| 2020-09-19 12:26:00 | E3 ubiquitin ligase RNF168, in addition to its canonical role in inhibiting end resection, acts in a redundant manner with BRCA1 to load PALB2 onto damaged DNA. Loss of RNF168 negates the synthetic rescue of BRCA1 deficiency by 53BP1 deletion | 30704900 |
| 2020-09-12 16:04:00 | A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis. | 31533041 |
| 2020-08-15 19:04:00 | Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination. | 32424115 |
| Type | IDs |
|---|---|
| Synonymous | hRNF168 |
| Gene |
UniProtKB-ID:
RN168_HUMAN
UniprotKB:
Q8IYW5
UniParc:
UPI00000741D1
EMBL:
AK054732,
AC117490,
AK093113,
AC092933,
BC033791
Ensembl:
ENSG00000163961
KO:
hsa:165918
|
| Nucleutide sequences |
EMBL-CDS:
AAH33791.1,
BAC04060.1,
BAB70801.1
Ensembl_TRS:
ENST00000318037
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320898
RefSeq:
NP_689830.2
|
| Others |
UniRef100:
UniRef100_Q8IYW5
UniRef90:
UniRef90_Q8IYW5
UniRef50:
UniRef50_Q8IYW5
UniGene:
Hs.250648
CCDS:
CCDS3317.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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