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16576 Kif7

16576

Kif7

kinesin family member 7

protein-coding

Mus musculus

基因描述

Type Description
Definition kinesin family member 7

研究结论

Date Results Publications
2019-03-23 12:03:00 Evolutionarily selected sequence differences enable immotile KIF7 motors to function not as transporters but as microtubule-based tethers of signaling complexes. 29351996
2018-03-10 12:03:00 Kif7-deficient thymocytes were unable to interpret changes in the Hedgehog signal. In addition, Kif7-deficiency reduced cell-surface MHCII expression on thymic epithelial cells. 28445929
2017-04-29 12:14:00 Mouse UBR3 poly-ubiquitinates Kif7, the mammalian homologue of Cos2. Finally, loss of UBR3 up-regulates Kif7 protein levels and decreases Hh signaling in cultured cells. 27195754
2016-05-07 12:16:00 Our data suggest that Kif7 may function to regulate the maintenance of the respiratory airway architecture by controlling cellular density, cell proliferation, and cycle exit through its role as a microtubule associated protein. 26439735
2015-11-21 11:50:00 findings demonstrate that perturbations of Sufu and Kif7 affect Gli activity and recapitulate the full spectrum of vertebrate limb defects, ranging from severe truncation to polydactyly. 25581370

名称对应

Type IDs
Gene
UniProtKB-ID: E9QMU1_MOUSE, J3QNW9_MOUSE
UniprotKB: E9QMU1, J3QNW9
UniParc: UPI000274726B, UPI0001B02ACA
EMBL: AC158582
Ensembl: ENSMUSG00000050382
KO: mmu:16576
Nucleutide sequences
Ensembl_TRS: ENSMUST00000059836, ENSMUST00000184137, ENSMUST00000183846, ENSMUST00000178048
Protein sequencees
Ensembl_PRO: ENSMUSP00000061806, ENSMUSP00000139224, ENSMUSP00000136993, ENSMUSP00000139359
RefSeq: NP_034756.2, NP_001278151.1, XP_006540728.1, XP_006540729.1, XP_006540730.1, XP_006540731.1, XP_006540733.1
Others
UniRef100: UniRef100_J3QNW9, UniRef100_E9QMU1
UniRef90: UniRef90_E9QMU1, UniRef90_B7ZNG0
UniRef50: UniRef50_B7ZNG0
UniGene: Mm.101633

全选

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