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165721 DNAJB8

165721

DNAJB8

DnaJ heat shock protein family (Hsp40) member B8

protein-coding

Homo sapiens

基因描述

Type Description
Definition DnaJ heat shock protein family (Hsp40) member B8

研究结论

Date Results Publications
2021-02-27 13:52:00 Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone. 33574241
2018-08-25 11:55:00 DNAJB8 is a central and versatile player in the protein aggregation and degradation system.DNAJB8 protein keeps Parkin C289G mutant protein in a soluble, degradation-competent form. 27713507
2018-03-17 10:37:00 Results show that DNAJB8 expression is induced by heat shock stress which increases side population cells and cancer stem-like cells. 29316077
2014-06-07 10:26:00 Taken together, the results indicate that DNAJB8 is expressed and has role in CRC CSC/CIC and that DNAJB8 is a novel target of CRC CSC/CIC-targeting immunotherapy. 24450541
2013-08-31 12:04:00 The mechanism of DNAJB6 and DNAJB8 is suppression of polyQ protein aggregation by directly binding the polyQ tract. 23612975

名称对应

Type IDs
Synonymous CT156, DJ6
Gene
UniProtKB-ID: DNJB8_HUMAN, A0A140VJI2_HUMAN
UniprotKB: Q8NHS0, A0A140VJI2
UniParc: UPI0000129437
EMBL: BC029521, CH471052, BC050288, AK126068, HM005369, AK125946
Ensembl: ENSG00000179407
KO: hsa:165721
Nucleutide sequences
EMBL-CDS: EAW79320.1, BAG54269.1, AAH29521.1, AAH50288.1, BAG54285.1, AEE60969.1
Ensembl_TRS: ENST00000469083, ENST00000319153
Protein sequencees
Ensembl_PRO: ENSP00000417418, ENSP00000316053
RefSeq: NP_699161.1, XP_006713582.1
Others
UniRef100: UniRef100_Q8NHS0
UniRef90: UniRef90_Q8NHS0
UniRef50: UniRef50_Q8NHS0
UniGene: Hs.518241
CCDS: CCDS3048.1

全选

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