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16571 Kif4

16571

Kif4

kinesin family member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition kinesin family member 4

研究结论

Date Results Publications
2020-12-12 13:25:00 Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells. 31486502
2020-01-11 11:04:00 This work reveals essential roles for Kif4 during the meiotic divisions. 31067151
2018-10-27 10:45:00 KIF4 was first found in neuron, then in chromatin and later in cytoplasm. It is expressed in various types of cells including cancer cells and germ cells. KIF4 also showed dynamic changes throughout the cell cycle. It is abnormally expressed in many cancers. [review] 30081192
2017-08-19 10:53:00 Further investigation of the phosphoregulation of meiotic Kif4 revealed that Aurora Kinase and Cdk activity is critical for Kif4 kinetochore localization and interaction with Ndc80 and CENP-C. Finally, Kif4 protein but not gene expression was found to be upregulated with age, suggesting a role for this protein in the decline of oocyte quality with age 28125646
2017-07-01 12:52:00 the silencing of Kif4 regulated VRGFR1 mRNA transcription and sVEGFR1 production in monocytes via the PI3K/Akt signaling pathway, which may be one of the mechanisms responsible for these processes. 28350061

名称对应

Type IDs
Synonymous AI323435, D330050K22Rik, Kns4
Gene
UniProtKB-ID: KIF4_MOUSE
UniprotKB: P33174
UniParc: UPI000018CE49
EMBL: BX276129, BC050946, D12646, BX005480, CH466564
Ensembl: ENSMUSG00000034311
KO: mmu:16571
Nucleutide sequences
EMBL-CDS: EDL14171.1, AAH50946.1, BAA02167.1
Ensembl_TRS: ENSMUST00000048962
Protein sequencees
Ensembl_PRO: ENSMUSP00000048383
RefSeq: NP_032472.2, XP_006527918.1, XP_017173886.1, XP_011245830.1
Others
UniRef100: UniRef100_P33174
UniRef90: UniRef90_P33174
UniRef50: UniRef50_P33174
UniGene: Mm.383091
CCDS: CCDS30305.1

全选

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