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16563 Kif2a

16563

Kif2a

kinesin family member 2A

protein-coding

Mus musculus

基因描述

Type Description
Definition kinesin family member 2A

研究结论

Date Results Publications
2019-08-17 11:14:00 These results suggested that postnatal KIF2A is a key length regulator of DGC developing neurites and is involved in the establishment of precise postnatal hippocampal wiring. 29313800
2019-07-13 11:14:00 Study in mutant mice and human cerebral organoids showed that WDR62 deletion resulted in a reduction in the size of mouse brains and organoids due to the disruption of neural progenitor cells. WDR62 interacts with and promotes CEP170 localization to the basal body of primary cilium, where CEP170 recruits KIF2A to disassemble cilium. 31197141
2019-03-09 11:40:00 Heterodimeric KIF3AC and KIF3AB, two members of the mammalian kinesin-2 family, generate force for microtubule plus end-directed cargo transport. This study reveals the impact of heterodimerization of the motor polypeptides for microtubule association to start the processive run and the fundamental differences in the motile properties of KIF3C compared with KIF3A and KIF3B. 29991594
2018-06-23 11:04:00 These data indicate that KIF2A regulates the spindle assembly, asymmetric cytokinesis and the metaphase I-anaphase I transition in mouse oocyte. 27991556
2018-06-09 10:55:00 Kif2a may act as a microtubule depolymerase, regulating microtubule dynamics, spindle assembly and chromosome congression, and thus cell cycle progression during mouse oocyte meiotic maturation. 27991495

名称对应

Type IDs
Synonymous C530030B14Rik, Kif2, Kns2, M-kinesin
Gene
UniProtKB-ID: KIF2A_MOUSE, E0CZ72_MOUSE, Q9D481_MOUSE
UniprotKB: P28740, E0CZ72, Q9D481
UniParc: UPI000019445C, UPI00001E8054, UPI000002549E, UPI00001E8050, UPI0000021CB1
EMBL: AC154257, BC006803, D12644, AK016720, AC154328, Y15894
Ensembl: ENSMUSG00000021693
KO: mmu:16563
Nucleutide sequences
EMBL-CDS: BAA02165.1, AAH06803.2, CAA75815.1, BAB30397.1
Ensembl_TRS: ENSMUST00000022204, ENSMUST00000117423, ENSMUST00000122233, ENSMUST00000159772
Protein sequencees
Ensembl_PRO: ENSMUSP00000113921, ENSMUSP00000112715, ENSMUSP00000022204, ENSMUSP00000125644
RefSeq: NP_001361656.1, NP_032468.2, XP_036013770.1, NP_001365866.1, NP_001365868.1, NP_001139251.1, NP_001365865.1, NP_001365867.1, XP_036013771.1, NP_001365869.1
Others
UniRef100: UniRef100_Q9D481, UniRef100_P28740, UniRef100_E0CZ72
UniRef90: UniRef90_A0A2K5CYN3, UniRef90_O00139
UniRef50: UniRef50_O00139, UniRef50_G3QCP3
UniGene: Mm.355686
CCDS: CCDS26759.1, CCDS49356.1

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