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16548 Khk

16548

Khk

ketohexokinase

protein-coding

Mus musculus

基因描述

Type Description
Definition ketohexokinase

研究结论

Date Results Publications
2019-09-14 12:31:00 studies suggest that it is the inhibition of the Khk C isoform, not the A isoform, that protects animals from Hereditary fructose intolerance. 29533924
2019-09-07 12:24:00 Manual correction of the input Khk gene model provided a much more accurate estimation of relative Khk isoform expression when compared to quantitative PCR. 31001414
2019-02-23 11:02:00 These results suggest that KHK-C might play a deleterious role in diabetic kidney disease progression through endogenous fructose metabolism, and that KHK-A plays a unique protective role against the development of diabetic kidney disease. 29604362
2017-09-23 12:35:00 This studies provided the first evidence that fructokinase modulates vasopressin synthesis in the SON and secretion from the posterior pituitary into circulation. 27852737
2017-07-29 10:34:00 Fructokinase knockout mice were protected from renal injury both at baseline and after high salt intake (3 wk) compared with wild-type mice. This was associated with higher levels of active (phosphorylated serine 1177) endothelial nitric oxide synthase in their kidneys. 27465991

名称对应

Type IDs
Gene
UniProtKB-ID: KHK_MOUSE, A0A0J9YU79_MOUSE, A0A0J9YUK6_MOUSE, E9Q1Q9_MOUSE
UniprotKB: P97328, A0A0J9YU79, A0A0J9YUK6, E9Q1Q9
UniParc: UPI0001548C8B, UPI0000028CE4, UPI00001F2203, UPI000016CA10
EMBL: AC109606, Y09335, BC013464
Ensembl: ENSMUSG00000029162
KO: mmu:16548
Nucleutide sequences
EMBL-CDS: CAA70515.1, AAH13464.1
Ensembl_TRS: ENSMUST00000201621, ENSMUST00000201571, ENSMUST00000031053
Protein sequencees
Ensembl_PRO: ENSMUSP00000144050, ENSMUSP00000144226, ENSMUSP00000031053
RefSeq: XP_006503811.1, NP_001297454.1, NP_001297453.1, NP_001335995.1, NP_032465.2
Others
UniRef100: UniRef100_P97328, UniRef100_A0A0J9YUK6, UniRef100_E9Q1Q9, UniRef100_A0A0J9YU79
UniRef90: UniRef90_E9Q1Q9, UniRef90_A0A0J9YUK6, UniRef90_P97328
UniRef50: UniRef50_F7B557, UniRef50_P97328, UniRef50_P50053
UniGene: Mm.22451
CCDS: CCDS39050.1

全选

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