| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel, subfamily Q, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:56:00 | Heterozygous loss of epilepsy gene KCNQ2 alters social, repetitive and exploratory behaviors. | 31283873 |
| 2020-05-23 11:53:00 | The ionic mechanism driving increased excitability involves alterations of the expression levels of HCN and KCNQ channel genes leading to a complex dynamic of H-current and M-current activation. Moreover, there is a negative correlation between the disease onset and disease progression, which correlates with a decrease in the expression level of HCN and KCNQ channels. | 30952836 |
| 2019-02-16 11:04:00 | decreases in interneuron KCNQ2/3 activity remodels excitatory networks, providing a new function for these channels. | 30382937 |
| 2017-08-19 12:55:00 | The data of this study showed that, in Kcnq2 mutant slices, burst activity was modulated by GABAA receptor blockade. | 28575529 |
| 2017-08-05 10:42:00 | Kcnq2 ablation leads to increased neuronal excitability of neocortex layer 2/3 pyramidal neurons. | 28100740 |
| Type | IDs |
|---|---|
| Synonymous | HNSPC, KQT2, Nmf134 |
| Gene |
UniProtKB-ID:
KCNQ2_MOUSE,
B7ZBV6_MOUSE,
Q3UY10_MOUSE,
B7ZBV5_MOUSE,
B7ZBV4_MOUSE,
B7ZBV7_MOUSE,
B7ZBW1_MOUSE,
B7ZBW2_MOUSE,
B7ZBV9_MOUSE,
B7ZBV8_MOUSE,
A0A0G2JFQ2_MOUSE
UniprotKB:
Q9Z351,
B7ZBV6,
Q3UY10,
B7ZBV5,
B7ZBV4,
B7ZBV7,
B7ZBW1,
B7ZBW2,
B7ZBV9,
B7ZBV8,
A0A0G2JFQ2
UniParc:
UPI00005ABB47,
UPI000058B139,
UPI0000028484,
UPI00004542FB,
UPI000002A676,
UPI000002A674,
UPI00004542FC,
UPI000002A67B,
UPI000002A677,
UPI000052D216,
UPI0000029899,
UPI000049E2FF,
UPI00001EE999,
UPI000002A67C,
UPI000002A679,
UPI00000287A8,
UPI000002A67A,
UPI0000356153,
UPI0000EF8892,
UPI000002A678,
UPI0000D77A30,
UPI000002A675,
UPI000016C737
EMBL:
AB000495,
AB000499,
AB000498,
AB000504,
BC145453,
AB000496,
AB000500,
AB000497,
AB000502,
AB000494,
AK139411,
AK135059,
AB000503,
AL450341,
AF490773,
AB000501
Ensembl:
ENSMUSG00000016346
KO:
mmu:16536
|
| Nucleutide sequences |
EMBL-CDS:
BAA37156.1,
BAA37160.1,
AAM09696.1,
BAE24000.1,
BAA37161.1,
BAA37158.1,
BAA37157.1,
BAA37166.1,
BAA37165.1,
BAA37162.1,
BAA37159.1,
BAA37164.1,
BAA37163.1,
BAE22403.1,
AAI45454.1
Ensembl_TRS:
ENSMUST00000049792,
ENSMUST00000081528,
ENSMUST00000016491,
ENSMUST00000103048,
ENSMUST00000103051,
ENSMUST00000103050,
ENSMUST00000149964,
ENSMUST00000103047,
ENSMUST00000197015
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000052453,
ENSMUSP00000080243,
ENSMUSP00000016491,
ENSMUSP00000099337,
ENSMUSP00000099340,
ENSMUSP00000099339,
ENSMUSP00000122915,
ENSMUSP00000099336,
ENSMUSP00000143263
RefSeq:
XP_006500630.1,
XP_017171229.1,
XP_017171262.1,
XP_017171270.1,
XP_017171242.1,
XP_017171265.1,
XP_036014669.1,
XP_006500631.1,
XP_036014673.1,
XP_011238227.1,
XP_036014665.1,
XP_030103657.1,
NP_001006669.1,
XP_017171224.1,
XP_017171230.1,
XP_006500628.1,
XP_017171227.1,
XP_017171232.1,
NP_001006675.1,
XP_017171240.1,
NP_001289817.1,
XP_030103635.1,
NP_001006670.1,
XP_017171260.1,
NP_001003825.1,
NP_001003824.1,
XP_017171243.1,
XP_030103629.1,
XP_017171231.1,
XP_017171261.1,
XP_030103658.1,
XP_030103648.1,
XP_030103632.1,
NP_034741.2,
XP_017171235.1,
XP_017171256.1,
XP_017171252.1,
XP_017171233.1,
XP_017171236.1
|
| Others |
UniRef100:
UniRef100_B7ZBV4,
UniRef100_Q9Z351,
UniRef100_B7ZBV6,
UniRef100_B7ZBV7,
UniRef100_B7ZBW1,
UniRef100_B7ZBV9,
UniRef100_B7ZBV8,
UniRef100_Q3UY10,
UniRef100_A0A0G2JFQ2,
UniRef100_B7ZBV5,
UniRef100_B7ZBW2
UniRef90:
UniRef90_B7ZBV9,
UniRef90_B7ZBV8,
UniRef90_A0A0G2JFQ2,
UniRef90_O43526,
UniRef90_Q9Z351-5,
UniRef90_B7ZBV4,
UniRef90_Q3UY10,
UniRef90_B7ZBV7,
UniRef90_Q9Z351
UniRef50:
UniRef50_A0A337S4D5,
UniRef50_A0A091NXN2,
UniRef50_F1PER0,
UniRef50_Q9Z351,
UniRef50_Q9Z351-5,
UniRef50_O43526
UniGene:
Mm.40615,
Mm.440175
CCDS:
CCDS17196.1,
CCDS17194.1,
CCDS17195.1,
CCDS17198.1,
CCDS17197.1,
CCDS17193.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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