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16535 Kcnq1

16535

Kcnq1

potassium voltage-gated channel, subfamily Q, member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium voltage-gated channel, subfamily Q, member 1

研究结论

Date Results Publications
2020-06-06 13:37:00 KCNQ/M-channels play a role in regulating the excitability of vagal airway C-fibers at both the cell soma and nerve terminals. 30721152
2020-05-30 10:14:00 It was concluded that KCNE2 regulates KCNQ1 in the lungs and is required for normal lung function and resistance to pulmonary ischemia/reperfusion injury. 31162977
2020-02-08 12:16:00 As a consequence of KCNQ1 haploinsufficiency, these variants also cause LQTS on both maternal and paternal transmission. These results are consistent with the hypothesis that, similar to what has been demonstrated in mouse, lack of transcription across IC2 results in failure of methylation establishment in the female germline and BWS later in development, and also suggest a new link between LQTS and BWS that. 30635621
2019-06-29 11:10:00 isoenzyme mediates the inhibitory action of Angiotensin II on slowly activating delayed rectifier K(+) curren and by phosphorylating distinct sites in KCNQ1/KCNE1, and duanyu1531epsilon isoenzymes produce the contrary regulatory effects on the channel. 29452158
2019-04-20 10:51:00 A double mutant mouse lacking both KCNQ1-KCNE3 and TASK-2 showed a much reduced cAMP-mediated anion secretion compared to that observed in the single KCNQ1-KCNE3 deficient mouse. 29143340

名称对应

Type IDs
Synonymous AW559127, KVLQT1, Kcna9
Gene
UniProtKB-ID: KCNQ1_MOUSE
UniprotKB: P97414
UniParc: UPI0000435847, UPI00001B3C82
EMBL: BC045142, BC055304, AK154244, AJ002201, AY331142, U70068
Ensembl: ENSMUSG00000009545
KO: mmu:16535
Nucleutide sequences
EMBL-CDS: AAP93874.1, AAH45142.2, AAB36518.1, CAA05246.1, BAE32460.1, AAH55304.1
Ensembl_TRS: ENSMUST00000009689
Protein sequencees
Ensembl_PRO: ENSMUSP00000009689
RefSeq: XP_006508554.3, XP_006508555.1, NP_032460.2, XP_006508551.2, XP_006508552.2, XP_011240284.2, XP_006508553.3, XP_036008611.1, XP_017177487.1
Others
UniRef100: UniRef100_P97414
UniRef90: UniRef90_Q9Z0N7
UniRef50: UniRef50_P51787-2
UniGene: Mm.439769, Mm.453036, Mm.453037
CCDS: CCDS22039.1

全选

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