| Type | Description |
|---|---|
| Definition | UBX domain protein 2A |
| Date | Results | Publications |
|---|---|---|
| 2019-08-10 12:42:00 | The existence of a multiprotein complex containing UBXN2A, CHIP, and mot-2 suggests a synergistic tumor suppressor activity of UBXN2A and CHIP in mot-2-enriched tumors. | 30107089 |
| 2016-12-17 10:04:00 | UBXN2A binds to mortalin's binding pocket within the substrate-binding domain of mortalin. UBXN2A increases stability of p53 protein targeted by the mortalin-CHIP E3 ubiquitin ligase. | 26634371 |
| 2016-08-13 11:50:00 | veratridine enhances transactivation of UBXN2A, resulting in upregulation of UBXN2A in the cytoplasm, where UBXN2A binds and inhibits the oncoprotein mortalin-2 | 26188124 |
| 2014-10-25 10:57:00 | Suggest UBXN2A can reconstitute inactive p53-dependent apoptotic pathways in colonic neoplasms. | 24625977 |
| 2013-01-26 10:21:00 | Ubx2 and Ubxd8 regulates lipid droplet homeostasis. | 22454508 |
| Type | IDs |
|---|---|
| Synonymous | UBXD4 |
| Gene |
UniProtKB-ID:
UBX2A_HUMAN
UniprotKB:
P68543
UniParc:
UPI000189A7C7,
UPI00001616AE
EMBL:
BC093681,
BC111997,
AC066692,
AL832079,
BC143298,
AK291192,
BC092484
Ensembl:
ENSG00000173960
KO:
hsa:165324
|
| Nucleutide sequences |
EMBL-CDS:
AAH92484.1,
BAF83881.1,
AAH93681.1,
AAI43299.1,
AAI11998.1
Ensembl_TRS:
ENST00000404924,
ENST00000309033
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000312107,
ENSP00000385525
RefSeq:
XP_005264223.1,
NP_859064.2,
XP_005264224.1,
XP_024308506.1,
XP_005264226.1,
XP_016859007.1,
XP_011530935.1,
XP_016859006.1,
XP_005264225.1
|
| Others |
UniRef100:
UniRef100_P68543
UniRef90:
UniRef90_P68543
UniRef50:
UniRef50_P68543
UniGene:
Hs.591576
CCDS:
CCDS1704.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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