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16532 Kcnu1

16532

Kcnu1

potassium channel, subfamily U, member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium channel, subfamily U, member 1

研究结论

Date Results Publications
2020-03-14 10:47:00 Study confirms that expression of full-length Slo3 is sperm-specific but warns against developing contraceptive drugs targeting the C-terminal tail of Slo3 channels. 31270758
2015-10-24 11:31:00 Considering that capacitation-induced hyperpolarization is mediated by SLO3, we evaluated the action of cSrc inhibitors on the heterologously expressed SLO3 channel. 26060254
2015-05-02 12:57:00 These results establish a critical role of LRRC52 in KSPER channels and demonstrate that loss of a non-pore-forming auxiliary subunit results in severe fertility impairment. 25675513
2015-01-24 11:49:00 SLO3 K+ channels have a role in controlling calcium entry through CATSPER channels in sperm 25271166
2014-05-03 10:47:00 Using mice lacking both SLO3 and CATSPER1 subunits, the results show conclusively that the voltage-activated outward current present in Slo3 (-/-) sperm is abolished when CATSPER is also deleted. 23980198

名称对应

Type IDs
Synonymous Kcnma3, Slo3, mSlo3
Gene
UniProtKB-ID: KCNU1_MOUSE, G3X9P7_MOUSE
UniprotKB: O54982, G3X9P7
UniParc: UPI0000357E79, UPI0000695DA6
EMBL: AC122752, AF039213
Ensembl: ENSMUSG00000031576
KO: mmu:16532
Nucleutide sequences
EMBL-CDS: AAB99742.2
Ensembl_TRS: ENSMUST00000098858
Protein sequencees
Ensembl_PRO: ENSMUSP00000096457
RefSeq: XP_006509087.1, XP_017168072.1, NP_032458.3, XP_017168071.1, XP_017168070.1
Others
UniRef100: UniRef100_O54982, UniRef100_G3X9P7
UniRef90: UniRef90_O54982
UniRef50: UniRef50_O54982
UniGene: Mm.289679
CCDS: CCDS52530.1

全选

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