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165140 OXER1

165140

OXER1

oxoeicosanoid receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition oxoeicosanoid receptor 1

研究结论

Date Results Publications
2019-06-08 10:40:00 The G protein coupled oxo-eicosanoid receptor 1 (OXER1) (a receptor of the arachidonic acid metabolite, 5-oxoeicosatetraenoic acid, 5-oxoETE) is as a novel mAR involved in the rapid effects of androgens. 30707908
2018-11-10 11:56:00 These findings verify that membrane-acting androgens exert specific effects through an antagonistic interaction with OXER1. Additionally, this interaction between androgen and OXER1, which is an arachidonic acid metabolite receptor expressed in prostate cancer, provides a novel link between steroid and lipid actions and renders OXER1 as new player in the disease. 28290516
2016-02-13 11:45:00 membrane receptor OxeR1 is involved in StAR protein induction and activation of steroidogenesis triggered by cAMP or angiotensin II, acting, at least in part, through ERK1/2 activation. 25657046
2014-06-28 13:02:00 Gue1654 as a non-Galphai-biased antagonist of OXE-R that provides a new basis for therapeutic intervention in inflammatory diseases that involve activation of eosinophils, neutrophils, and monocytes. 24733850
2013-08-31 12:04:00 OXER1 has a role in regulating the survival-promoting effects of arachidonate 5-lipoxygenase in prostate cancer cells 23643940

名称对应

Type IDs
Synonymous GPCR, GPR170, TG1019
Gene
UniProtKB-ID: OXER1_HUMAN
UniprotKB: Q8TDS5
UniParc: UPI000003BCC9
EMBL: AB065652, BC063549, AB083630, AC098824, AB083055, AY158687
Ensembl: ENSG00000162881
KO: hsa:165140
Nucleutide sequences
EMBL-CDS: BAC11806.2, AAY14700.1, AAO17739.1, BAC05878.1, BAB89343.1, AAH63549.1
Ensembl_TRS: ENST00000378661
Protein sequencees
Ensembl_PRO: ENSP00000367930
RefSeq: NP_683765.1
Others
UniRef100: UniRef100_Q8TDS5
UniRef90: UniRef90_Q8TDS5
UniRef50: UniRef50_Q8TDS5
UniGene: Hs.168439
CCDS: CCDS1810.1

全选

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