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16511 Kcnh2

16511

Kcnh2

potassium voltage-gated channel, subfamily H (eag-related), member 2

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium voltage-gated channel, subfamily H (eag-related), member 2

研究结论

Date Results Publications
2020-09-19 16:29:00 Identification and Characterization of a Transcribed Distal Enhancer Involved in Cardiac Kcnh2 Regulation. 31484079
2019-06-29 10:38:00 These results indicate that hERG is a substrate of HDAC6. 29355491
2018-08-18 10:05:00 PKD1 mediates the effects on KV11.1 and we found that PKD targets S284 in the N-terminus of the channel. 29949809
2018-01-06 12:45:00 histone H4 hyperacetylation induced by Class I HDACs inhibitors promoted the expression profiles of potassium channels (Kcnj2, Kcnj3, Kcnj5, Kcnj11, and Kcnh2) 28464250
2016-12-17 10:12:00 Using a combination of mouse genetics, biochemistry, molecular and cell biology, we demonstrate that Nkx2-5 regulates the gene encoding Kcnh2 channel and others, shedding light on potential mechanisms generating electrical abnormalities observed in patients bearing NKX2-5 dysfunction and opening opportunities to the study of novel therapeutic targets for anti-arrhythmogenic therapies 26897459

名称对应

Type IDs
Synonymous AI326795, ERG1, LQT, Lqt2, M-erg, Merg1, merg1a, merg1b
Gene
UniProtKB-ID: KCNH2_MOUSE, Q53Z09_MOUSE, A0A0R4J1K0_MOUSE
UniprotKB: O35219, Q53Z09, A0A0R4J1K0
UniParc: UPI000016C7BE, UPI0000029451, UPI000002ACA5, UPI0000023E58, UPI000002ACA6
EMBL: AC113055, AF034762, AF012871, AF012868, AF012870, AF012869, AY374424
Ensembl: ENSMUSG00000038319
KO: mmu:16511
Nucleutide sequences
EMBL-CDS: AAC53421.1, AAC53422.1, AAC53419.1, AAC53420.1, AAC53418.1, AAB87571.1, AAQ82708.1
Ensembl_TRS: ENSMUST00000036092, ENSMUST00000115098
Protein sequencees
Ensembl_PRO: ENSMUSP00000047705, ENSMUSP00000110750
RefSeq: XP_006535696.1, XP_006535695.1, XP_006535697.1, NP_001281091.1, XP_006535698.1, NP_038597.2
Others
UniRef100: UniRef100_Q53Z09, UniRef100_O35219, UniRef100_A0A0R4J1K0
UniRef90: UniRef90_O35219-3, UniRef90_Q12809-4
UniRef50: UniRef50_Q12809, UniRef50_O35219-3
UniGene: Mm.6539
CCDS: CCDS80224.1, CCDS19116.1

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