| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel, subfamily H (eag-related), member 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-20 10:12:00 | n this report, we present two independent screening campaigns in which we wanted to identify small molecules that bind to either the intracellular cytoplasmic amino terminal Per-Arnt-Sim (PAS) domain from the human EAG-related gene (ERG) channel or the amino or carboxy terminal globular domains from the mouse EAG1 channel, affecting their interaction. | 26975997 |
| 2017-08-19 12:55:00 | KV10.1 localizes to the centrosome and the primary cilium and promotes ciliary disassembly. Interference with KV10.1 ciliary localization abolishes not only the effects on ciliary disassembly, but also KV10.1-induced tumor progression in vivo Conversely. | 27113750 |
| 2016-12-17 10:59:00 | Expression of Kv10.1 driven by phosphorylated Rb/E2F1 contributes to G2/M progression of cancer and non-transformed cells. | 27029528 |
| 2015-09-12 10:21:00 | KV 10.1 opposes activity-dependent increase in calcium influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse | 25556795 |
| 2014-01-04 10:10:00 | deletion of Kv10.1 does not show a marked phenotype is a prerequisite for utilizing Kv10.1 blocking and/or reduction techniques, such as siRNA, to treat cancer. | 23424202 |
| Type | IDs |
|---|---|
| Synonymous | EAG1, Kv10.1, M-eag |
| Gene |
UniProtKB-ID:
KCNH1_MOUSE,
A0A1L1M1J8_MOUSE,
Q3UHC9_MOUSE
UniprotKB:
Q60603,
A0A1L1M1J8,
Q3UHC9
UniParc:
UPI00005AC663,
UPI000002816B,
UPI00005DC6F3
EMBL:
U04294,
AC109240,
AK147461,
BC109013,
AC158791,
AC105325,
AK140193,
CH466555
Ensembl:
ENSMUSG00000058248
KO:
mmu:16510
|
| Nucleutide sequences |
EMBL-CDS:
EDL12967.1,
AAI09014.1,
BAE24272.1,
AAA62474.1,
BAE27928.1
Ensembl_TRS:
ENSMUST00000078470,
ENSMUST00000110844
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000077563,
ENSMUSP00000106468
RefSeq:
XP_036018166.1,
NP_001033696.1,
NP_034730.1,
XP_006497292.1
|
| Others |
UniRef100:
UniRef100_A0A1L1M1J8,
UniRef100_Q60603,
UniRef100_Q3UHC9
UniRef90:
UniRef90_O95259,
UniRef90_Q63472
UniRef50:
UniRef50_Q63472
UniGene:
Mm.4489
CCDS:
CCDS15627.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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