Type | Description |
---|---|
Definition | potassium voltage-gated channel, Shal-related family, member 2 |
Date | Results | Publications |
---|---|---|
2021-03-13 13:17:00 | The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice. | 32822706 |
2020-07-25 12:10:00 | Study uncovers increased levels of active GSK3beta in the nucleus accumbens (NAc) of mice with a depressive-like phenotype induced by chronic stress. Increased levels of active GSK3beta within the NAc of these mice lead to altered synaptic plasticity in medium spiny neurons through phosphorylation of the Kv4.2 subunit uncovering molecular mechanism of underlying depression-like behaviors. | 32209671 |
2020-07-18 11:39:00 | activity-induced Kv4.2 phosphorylation triggers Pin1 binding to, and isomerization of, Kv4.2 at the pThr(607)-Pro motif, leading to the dissociation of the Kv4.2-DPP6 complex. | 32218435 |
2020-07-18 10:33:00 | Results identify the functional interaction between GSK3beta and Kv4.2 channel as a novel mechanism for long-term depression modulation providing exciting insight into the understanding of GSK3beta role in synaptic plasticity. | 29790931 |
2019-08-24 11:29:00 | Kv4 interacting dynamically with persistent sodium currents is a key determinant of the irregular firing behaviour of Kiss1(Arc) neurons. | 29214635 |
Type | IDs |
---|---|
Synonymous | AI839615, AW555701, Kv4.2, R75121 |
Gene |
UniProtKB-ID:
KCND2_MOUSE
UniprotKB:
Q9Z0V2
UniParc:
UPI0000025EEC
EMBL:
AK032772,
BC079667,
AB093280,
AB045326,
AF107780,
AK032268
Ensembl:
ENSMUSG00000060882
KO:
mmu:16508
|
Nucleutide sequences |
EMBL-CDS:
AAH79667.1,
BAC27787.1,
BAC28015.1,
BAA97986.1,
BAC41464.1,
AAD16972.1
Gene_ORFName:
MNCb-7013
Ensembl_TRS:
ENSMUST00000081542
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080257
RefSeq:
XP_036021777.1,
NP_062671.1
|
Others |
UniRef100:
UniRef100_Q9Z0V2
UniRef90:
UniRef90_Q63881
UniRef50:
UniRef50_Q63881
UniGene:
Mm.425316
CCDS:
CCDS19934.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员